NFL Week 1 Bets: 5 best ATS bets to make

Analyzing the early sports betting odds and lines for Week 1 of the 2020 NFL season, picking the 5 best bets against the spread.

With the recent release of the 2020 NFL schedule, BetMGM posted lines for Week 1. Here are five of the best bets vs. the spread to make for Week 1 of the 2020 NFL season.

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Odds last updated Sunday, May 10 at 1:50 a.m. ET.

Best bet 1: Miami Dolphins (+6.5) at New England Patriots

Sunday, Sept. 13 (1 p.m. ET)

The Dolphins went out in the offseason and spent a bunch of money in free agency and also added talent in the draft. They still have a productive veteran starting quarterback in Ryan Fitzpatrick, while the Pats have lost many key players; most importantly, QB Tom Brady. The Dolphins aren’t as bad as they were a year ago and the Pats are not going to be as good.

Best bet 2: Arizona Cardinals (+8.5) at San Francisco 49ers

Sunday, Sept. 13 (4:25 p.m. ET)

The 49ers lost a key offensive weapon in WR Emmanuel Sanders and traded away DL DeForest Buckner. Even in their 13-3 season a year ago, they failed to cover the spread in both games vs. the Cardinals. Arizona added WR DeAndre Hopkins and upgraded its 31st-ranked defense from 2019.


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Best bet 3: New Orleans Saints (-4.5) vs. Tampa Bay Buccaneers

Sunday, Sept. 13 (4:25 p.m. ET)

The Bucs might have Brady at QB, but with a shortened offseason and a new offense that traditionally takes a few games for quarterbacks to adjust to, expect New Orleans to come out on fire. The Saints added another big weapon in the passing game in WR Sanders, while they still have QB Drew Brees, RB Alvin Kamara and WR Michael Thomas.

Best bet 4: Tennessee Titans (+2.5) at Denver Broncos

Monday, Sept. 14 (10:10 p.m. ET)

The Broncos added young receivers in the draft but the Titans were one of the hottest teams in the NFL after Ryan Tannehill took over at quarterback. Tannehill returns as does RB Derrick Henry. Tennessee will beat Denver, especially with Drew Lock at QB for the Broncos.

Best bet 5: Pittsburgh Steelers (-3.5) at New York Giants

Monday, Sept. 14 (7:15 p.m. ET)

The Steelers get QB Ben Roethlisberger back. The Giants still have questions around their defense. New York QB Daniel Jones has more protection, but the lack of an offseason with a new head coach will show in Week 1.

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