The 49ers will have to deal with Drew Brees and the Saints without a member of the secondary. Strong safety Jaquiski Tartt on Friday was officially ruled out with a broken rib he suffered in last week’s loss to the Ravens. Defensive tackle Jullian Taylor was also ruled out.

Second-year safety Marcell Harris played well filling in for Tartt when the starter went down in Baltimore. Harris’ strip and fumble recovery on Ravens quarterback Lamar Jackson swung the tide of the game briefly in the 49ers’ favor. Harris will start in Tartt’s stead against the Saints.

Taylor injured his elbow and was expected to be ruled out for Week 14 and Week 15. His status beyond the next couple weeks is uncertain.

The good news on the 49ers’ injury report was the players missing from it. Offensive tackle Joe Staley is officially questionable after limited practices all week. He’s still working his way back from finger surgery. Defensive end Dee Ford,  defensive tackle DJ Jones and running back Matt Breida should all play against New Orleans.

There was optimism from head coach Kyle Shanahan that those three would be good to go against the Saints, and a week of practice validated that positivity. All three were full participants in Friday’s practice and will be ready to go Sunday.

Shanahan was less optimistic about wide receiver Dante Pettis returning from a knee injury. He’s officially questionable, alongside fellow wide receiver Marquise Goodwin. Goodwin was a late add to the status report with knee and foot injuries.

Defensive lineman Kentavius Street still hasn’t been activated off Injured Reserve, although his practice window did open. He can still be added to the roster Saturday if the team believes he’s ready to make his NFL debut.

Here’s the full status report:

Out

S Jaquiski Tartt (ribs)
DL Jullian Taylor (elbow)

Questionable

WR Dante Pettis (knee)
WR Marquise Goodwin (knee, foot)
OT Joe Staley (finger)