After having an extended break following last Thursday’s game against the Houston Texans, the Indianapolis Colts return to action as they’ll host the Tennessee Titans on Sunday. They approach the end of this three-week stretch, which consisted of all divisional matchups.

Even with their loss in Week 12 and suffering additional injuries, the Colts are still very much alive in the AFC playoff picture. It’s just a matter of relying on their strengths at this point, and hopefully getting back a key contributor or two in the coming weeks.

Here are three, key matchups to watch in the Colts’ Week 13 bout against the Titans:

QB Jacoby Brissett vs. Titans’ Top 10 scoring defense

Even as someone who has defended Jacoby Brissett on various occasions, I must admit now is the time for him to step up his game. Regardless if it was before his knee injury in Week 9 or right after, the Colts’ QB1 has begun to struggle and is in need of a huge game on Sunday.

While the Titans rank fairly low in defensive categories such as passing yards allowed (24th with 255) and red-zone scoring percentages (30th with 64.5%), they’ve been a stingy group in other areas. Entering Week 13, the Titans have been giving up the ninth and eighth fewest points per game and third-down conversions, respectively. This is huge to think about in relation to Brissett’s struggles.

For a quarterback that has averaged 138 passing yards in his last two games along with being sacked four times, the odds seem to be against Brissett having a breakout game. Especially when he’ll be missing his three best offensive targets in RB Marlon Mack, WR T.Y. Hilton, and TE Eric Ebron.