Tyrann Mathieu Tackles/Assists

Over – Under 5.5

If you’ve watched Mathieu play at all this season, you’d know he’s been all over the field. He’s everywhere. He’s coming up to the line to stop the run — and he will have to do that this week — and he’s making plays down the field in the passing game. He rarely misses tackles in the open field.

This one almost seems too easy. Take the over and don’t think about it. The Chiefs should use Mathieu’s ability close to the line to stop the Niners running game and make life difficult for George Kittle.