49ers favored over Giants despite injury issues

Injury issues on both sides leave the 49ers as four-point favorites vs. the Giants at MetLife Stadium.

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The 49ers’ injury woes didn’t stop oddsmakers from making them favorites over the winless New York Giants. BetMGM Sportsbook has San Francisco favored by 4 points Sunday on the road at MetLife Stadium.

One key reason for that line is the Giants’ injury issues. They’ll be without running back Saquon Barkley, who tore his ACL last week. Wide receiver Sterling Shepard also went on Injured Reserve with a toe injury.

San Francisco on the other hand will be down running backs Raheem Mostert and Tevin Coleman, and defensive ends Nick Bosa and Dee Ford. They’ll likely not have quarterback Jimmy Garoppolo, and tight end George Kittle’s status is still uncertain. Deebo Samuel and Richard Sherman are also on Injured Reserve.

It’s a testament to the depth of the 49ers’ roster that they’re still more than a point or two road favorites with so many players sidelined. The Giants are 0-2, but their defense has been respectable to this point. Their offense has been less formidable.

This is a game the 49ers should be able to win even with their growing list of injuries. In a normal setting they may win going away. The injuries on both sides make this such a high-variance contest that it’s hard to get a feel for how the game goes either way. It’ll also be interesting to see if the line changes once official injury announcements are made on Kittle and Garoppolo.

This is a stay away for us from a wagering perspective, but the Giants getting 4 is our guess if we had to make one.

[Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage.]

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