The 49ers visit Baltimore on Sunday for the second phase of their three-game stretch against teams with winning percentages of .800 or better. They’ll have a tough task trying to slow down the highest-scoring offense in the league, led by quarterback Lamar Jackson. San Francisco’s offense also faces a tall task against a Ravens defense that’s allowed just 11.5 points per game in their last four.

Here are the three matchups that matter most in Baltimore:

Robert Saleh vs. Lamar Jackson

Saleh will have to figure out how to do something not many teams have been able to this season: put together a game plan to slow down Jackson. Slowing him is the key to keeping Baltimore from racking up 30-plus points–  something they’ve done six times this season.

If there’s any defensive coordinator that can do it, it’s Saleh. Saleh was able to put together a plan last week that held Aaron Rodgers to just 104 passing yards and his worst-ever yards per attempt. It could be game of adjustments for Saleh and the defense, but they’ll need to play their best game of the season against Jackson and company.

Richard Sherman vs. Marquise Brown

Brown has been Jackson’s second-favorite target behind Mark Andrews, but Brown is by far his most explosive. It’s not easy to beat Sherman. Speed is one way teams have tried to attack the 31-year-old. Sherman has also had a penalty issue the past couple of weeks with five penalties, including three pass interferences, against Arizona and Green Bay. Sherman can thwart Brown’s speed with physicality, but that opens him up to those flags coming out.

Fred Warner vs. Mark Ingram

Lost in Jackson’s MVP-caliber season is Mark Ingram’s importance to the Ravens’ offense. Ingram is averaging a whopping 5.2 yards per carry and has nine rushing touchdowns. The 49ers have struggled against the run game all season, allowing 100 or more yards on the ground in nine of their 11 games. Warner has been good against the run while putting together an All-Pro caliber season in the middle of the 49ers’ defense. He has a team-high 81 tackles and six tackles for loss. Not only will Warner be important against a running Jackson, but also Ingram while trying to contain the league’s best running team.