10 Best College Football Predictions Against The Spread: Week 5

What college football games appear to be the best bets and the best picks against the spread going into Week 5?

4. USC at Colorado

LINE USC -7.5
ATS PICK USC

Which USC is going to show up?

It was okay against San Jose State to start the season, and then came the loss to Stanford.

The team perked up in time to roll past Washington State, and then the defense couldn’t seem to do anything right a home loss to Oregon State.

There’s no reason to trust the Trojans in any way right now, but they still have more talent than anyone other than – possibly – Oregon. They still have the firepower, and they still have the ability to end this that Colorado doesn’t.

The Buffaloes have been great at times defensively, but we’re now on three games in a row without coming up with more than 260 yards of total offense. They scored just 20 points in the last three games – USC might get that early on to put it away.

Minnesota rolled at will on Colorado – and then lost to Bowling Green. Arizona State came off a loss to BYU and pushed past the Buffs 35-13.

USC needs to stick with its pattern and follow up a loss with a win.

NEXT: College Football Pick Against The Spread No. 3: Oklahoma at Kansas State