WATCH: Tennessee Titans are a lock for NFL Week 5 | Lorenzo’s Locks

USA TODAY Sports’ Lorenzo Reyes offers up his three locks of the NFL’s Week 5 with his eyes on the Tennessee Titans.

Week 5 of the 2021 NFL season includes another full slate of Sunday matchups. USA TODAY Sports’ Lorenzo Reyes helps tee up this week’s biggest games with his NFL Week 5 locks. Visit SportsbookWire.com for our NFL picks and predictions.

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list.

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