WATCH: Arizona Cardinals at Tennessee Titans, Week 1, Key Facts, Stats

See betting lines, statistical trends and relevant facts for the 2021 season opener between the Arizona Cardinals and the Tennessee Titans.

The Arizona Cardinals kick off their season on the road, facing the Tennessee Titans. The road team won eight of the last nine season openers for the Titans, and Arizona will look to continue that trend in 2021. Tennessee is favored in this one, but the Cardinals have high hopes for DE J.J. Watt to make an immediate impact for the team. Go to Tipico Sportsbook for the most updated odds.

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