Vanderbilt at Missouri odds, picks and predictions

Analyzing Saturday’s Vanderbilt at Missouri odds and lines, with college football expert picks, predictions and best bets.

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The No. 8 Missouri Tigers (3-0, 0-0 SEC) welcome the Vanderbilt Commodores (2-1, 0-0) to Memorial Stadium for a conference clash Saturday. Kickoff is set for 4:15 p.m. ET (SEC Network). Let’s analyze BetMGM Sportsbook’s college football odds around the Vanderbilt vs. Missouri odds, and make our expert college football picks and predictions.

Missouri opened the season witha 51-0 win against the Murray State Racers and then a 38-0 win over the Buffalo Bulls. The Tigers had a closer call with Boston College in Week 3, winning 27-21. Missouri is 2-1 against the spread (ATS), having played all 3 games at home. It is 0-3 O/U as well.

Vanderbilt opened its season with a surprise 34-27 win over the Virginia Tech Hokies as a 13-point underdog. It then beat Alcorn State 55-0 and had a surprise Week 3 loss to Georgia State 36-32. Vanderbilt is 0-1 ATS on the road and 1-0 ATS as an underdog. The Commodores QBs have yet to throw an INT, having accumulated 560 yards and 5 TDs.

Missouri is No. 8 in the US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Vanderbilt at Missouri odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Friday at 6:12 p.m. ET.

  • Moneyline (ML): Vanderbilt +900 (bet $100 to win $900) | Missouri -1600 (bet $1,600 to win $100)
  • Against the spread (ATS): Vanderbilt +20.5 (-115) | Missouri -20.5 (-105)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Vanderbilt at Missouri picks and predictions

Prediction

Missouri 41, Vanderbilt 17

Moneyline

PASS.

There’s no reason to play Missouri (-1600) to win outright at home, especially considering Vanderbilt (+900) has played better than expected this season. The Tigers are too expensive to play on the moneyline.

Against the spread

BET MISSORUI -20.5 (-105).

The Tigers have destroyed opponents this season, especially when they’re favored by 20 points or more. Missouri is 2-0 ATS when a favorite by that number. While the Tigers beat Boston College by just 6, they did end with  120 more rushing yards. They were the better side and arguably should’ve won by enough to cover.

Similarly, Vanderbilt is coming off its worst game of the season and lost as an 8.5-point favorite. It has yet to play a team of Missouri’s caliber. It lost every road game last season and lost its last 4 on the road by 20 or more.

Expect the Tigers to come out on top with ease and back MISSOURI -20.5 (-105).

Over/Under

BET OVER 52.5 (-110).

This game is a battle between 2 polar opposites. The Commodores are 3-0 O/U while the Tigers are 0-2 O/U. The Commodores have scored 30 points or more in all 3 games and have allowed 27 points or more in 2 of 3.

The Tigers have a dynamic offense and have scored at least 38 points in 2 of 3 and 27 points or more in all 3. Missouri, in its lone game against a Power 4 side, gave up 21 points as well. Expect a high-scoring battle.

Play OVER 52.5 (-110).

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