USA TODAY Sports Network’s NFL Week 13 game previews, predictions

The USA TODAY Sports Network previews Week 13 in the NFL, with 49ers-Ravens, Patriots-Texans and Vikings-Seahawks leading the slate.

Tennessee Titans at Indianapolis Colts

Derrick Henry Tennessee Titans
Jeremy Brevard-USA TODAY Sports

TV: 1 p.m. ET Sunday, CBS

Records: Titans 6-5, Colts 6-5

Line: Colts by 2½

Titans’ keys: The offense revolves around getting RB Derrick Henry involved and running downhill. QB Ryan Tannehill must target TE Jonnu Smith because the Colts have struggled against tight ends.

Colts’ keys: In relief of injured Marlon Mack, RB Jonathan Williams must continue his dominance. He has rushed for 116 and 104 yards in his last two games.

Who wins? On the back of the defense and an improved passing attack, the Colts win a close one. Colts 21, Titans 19

Kevin Hickey