Upsets highlight ACC football early kickoff games in Week 6

It’s looking more and more like it’s Clemson vs. Miami for the ACC after Louisville fell to SMU on Saturday.

This story was updated to add new information. 

It’s looking more and more like a two-team race in the ACC between the Clemson Tigers and Miami Hurricanes.

The 22nd-ranked Louisville Cardinals, the league’s only other ranked team in Week 6, fell at home to the SMU Mustangs, 34-27, Saturday at L&N Federal Credit Union Stadium.

SMU (5-1) started hot and got out to a 24-13 lead at halftime. Louisville came to life in the second half but a critical stop by the Mustangs’ defense on 4th and 1 from the SMU 19-yard line early in the fourth quarter allowed SMU to take over on downs.

The Mustangs then drove 89 yards on 11 plays, highlighted by a 19-yard run by Brashard Smith that included a fumble that was initially awarded to Louisville but which was overturned on video review. Four plays later, LJ Johnson Jr. carried it into the end-zone from a yard out for a 34-27 SMU lead with 6:39 to play.

RELATED: What channel is Clemson vs Florida State on today? Time, TV schedule for Week 6 game

Tyler Slough was picked off in the end-zone on fourth down on the Cardinals’ next drive with 2:30 to play. SMU got two first downs to run out the clock for their seventh straight road victory dating back to last year.

Elsewhere in the early slate of ACC action, the NC State Wolfpack fell 34-30 to Wake Forest in Raleigh, giving Dave Doeren’s team three losses to fall to 3-3.

Boston College fell 24-14 in Charlottesville to the Virginia Cavaliers. Bill O’Brien’s Eagles fell to 4-2 while the Hoos improved to 4-1.

Clemson (3-1) takes on the Florida State Seminoles (1-4) at 7 p.m. ET at Doak Campbell Stadium. The game can be seen on ESPN.

RELATED: Staff score predictions for Clemson-Florida State Week 6 matchup

Following Clemson-Florida State, Miami (5-0) faces the California Golden Bears (3-1) beginning at 10:30 p.m. ET in Berkeley on ESPN.