Defense (28)
| Pos. | First | Second | Third |
| LDE | Alex Okafor | Demone Harris | Anthony Lanier |
| LDT | Chris Jones | Mike Pennel | Khalen Saunders, Braxton Hoyett |
| RDT | Derrick Nnadi | Breeland Speaks | Devaroe Lawrence |
| RDE | Frank Clark | Tanoh Kpassagnon | Tim Ward |
| LB | Anthony Hitchens | Ben Niemann | Darius Harris |
| LB | Damien Wilson | Dorian O’Daniel | Emmanuel Smith |
| LCB | Charvarius Ward | Chris Lammons | |
| RCB | Alex Brown | Antonio Hamilton | |
| CB | Rashad Fenton | ||
| FS | Juan Thornhill | Daniel Sorensen | |
| SS | Tyrann Mathieu | Armani Watts |
Observations:
- The Chiefs brought back defensive tackle Mike Pennel on a one-year deal. He worked his way up the depth chart in 2019, operating as the second-string DT behind Chris Jones. I’d expect that he remains in that spot for the 2020 season.
- Antonio Hamilton is another newcomer to the Chiefs. The cornerback depth is so thin that Hamilton’s existence gets him a second-string spot with the team. We’ll see what the future holds, but for now, it looks as if he’ll have a good chance to make the team.