The Tennessee Titans and Indianapolis Colts will meet for the first time in 2022 at Lucas Oil Stadium in Week 4. These two teams will have their final meeting in Week 7 in Nashville.
Pegged as the two best teams in the AFC South going into the season, the Titans and Colts have both struggled, leading to the upstart Jacksonville Jaguars grabbing the division lead after three games.
However, that may not last much longer, as a Jaguars loss to the Philadelphia Eagles will allow one of these two teams to either grab a share of (Titans) or sole possession of (Colts) first place in the division with a win.
The Titans have had Indy’s number in recent years, winning each of the last three contests and four of the last five.
Surprisingly, despite the Colts once again being the AFC South darlings in the eyes of experts ahead of 2022, the majority of them in our expert picks round-up are going with the Titans.
Does our staff feel the same way? Find out now as we make our picks and predictions for Week 4.