The early game day betting lines for Clemson vs. Louisville

Here’s a look at the early odds for Clemson’s matchup with Louisville.

Starting the 2022 college football season 8-1 (6-0 ACC), Dabo Swinney and the Tigers experienced their first loss, 35-14, last Saturday at the hands of Marcus Freeman and the Notre Dame Fighting Irish. 

It was the worst performance we’ve seen out of the Tigers this season, as they got outcoached and outplayed from start to finish. Clemson will head back home this week to take on a tough Louisville team that is getting hot at the right time, led by star quarterback Malik Cunningham. 

Even after the Tigers got beaten up by the Fighting Irish, they enter this matchup with Louisville as the betting favorite for the tenth straight game this season.

Wondering what the lines are looking like for the Tigers’ matchup with the Cadinals? We’ve got you covered with a look at all MGM Sportsbook’s lines for Clemson’s Week 10 game.

  • Point spread: Clemson -7.5
  • Clemson moneyline: N/A
  • Louisville moneyline: N/A
  • Over/Under: 51.5

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