The best-of-three series is scheduled to take place Saturday-Monday at Pete Taylor Park in Hattiesburg, Mississippi.
Neither team is a national seed, and neither hosted its regional. Both the Vols and Golden Eagles were No. 2 seeds in their respective regionals. That means it was left to the NCAA committee to determine Southern Miss would serve as the host to the super regional.
The winner between Tennessee and Southern Miss in the best-of-three series will advance to the College World Series.
How to watch Tennessee-Southern Miss NCAA Tournament super regional
Below are projected starting pitchers for the super regional between Tennessee and Southern Miss.