Xavier at DePaul odds, picks and predictions

Analyzing Wednesday’s Xavier at DePaul odds and lines, with college basketball expert picks, predictions and best bets.

The No. 8 Xavier Musketeers (15-3, 7-0 Big East) take on the DePaul Blue Demons (8-10, 2-5) Wednesday. Tip from Wintrust Arena is set for 8:30 p.m. ET (FS1). Below, we analyze Tipico Sportsbook’s lines around the Xavier vs. DePaul odds, and make our expert college basketball picks, predictions and bets.

Xavier took care of Marquette 80-76 Sunday, covering as a 3-point home favorite. Xavier has now covered the spread in 5 straight games and is 7-3 against the spread (ATS) in its last 10, improving to 11-6-1 ATS on the season. The Musketeers are one of the top offenses in the nation, ranking 11th in points per game (84.2), 3rd in field goal percentage (50.59%) and 5th in 3-point percentage (40.18%).

DePaul lost 71-67 to Seton Hall Saturday, but still covered as a 4.5-point home underdog. DePaul is 4-1-1 ATS in its last 6 and 5-4-1 ATS in its last 10 to improve to 9-8-1 ATS on the season. The Blue Demons have struggled on defense this year, ranking 274th in opponents’ field goal percentage (44.98%) and 287th in opponents’ 3-point field goal percentage (35.7%).

Rankings courtesy of the USA TODAY Sports Coaches Poll.

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Xavier at DePaul odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:55 a.m. ET.

  • Moneyline (ML): Xavier -400 (bet $400 to win $100) | DePaul +300 (bet $100 to win $300)
  • Against the spread (ATS): Xavier -8.5 (-115) | DePaul +8.5 (-105)
  • Over/Under (O/U): 157.5 (O: -105 | U: -115)

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Xavier at DePaul picks and predictions

Prediction

Xavier 89, DePaul 75

Moneyline

PASS.

There is no value on either team.

Against the spread

LEAN XAVIER -8.5 (-115).

Xavier has one of the top offenses in the nation and is squaring off against DePaul, who has one of the worst defenses in the nation. DePaul has been unable to defend the 3-pointer this season and that is one of the Musketeers’ strong suits.

Xavier has played great on the road this season, with a 4-0 straight-up record and a 4-0 ATS record.

The road team is 5-2 ATS in the last 7 matchups between these two.

Over/Under

BET OVER 157.5 (-105).

The Musketeers are 13-4-1 O/U this season and have scored 80 or more points in 8 of their last 10 games. The Over is 5-1 in their last 6 road games against a team with a winning home record, too.

Xavier’s defense has been their weak point this season, ranking 311th in opponents’ points per game (75.1) and DePaul’s defense ranks 306th in the same category, a perfect recipe for the OVER 157.5 (-105) play.

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