Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 1 gameday inactives, weather and notes
KEY GAME-TIME DECISIONS
Early games: WR Ja’Marr Chase, QB Russell Wilson, WR DeAndre Hopkins
Afternoon games: RB Antonio Gibson
Sunday night:
Monday night:
Early games
Pittsburgh Steelers at Atlanta Falcons (1:00 p.m. ET)
Kickoff Weather: 75°F, mostly clear (retractable-roof dome)
Steelers
Inactives:
Lineup notes: QB Russell Wilson (calf) is questionable after he was limited in practice Thursday and Friday. QB Justin Fields took Friday’s first-team reps and should draw the start. RB Jaylen Warren (hamstring) practiced Thursday and Friday and will suit up.
Falcons
Inactives:
Lineup notes: TE Kyle Pitts (hamstring) had a full session Thursday and Friday and escapes an injury designation.
Arizona Cardinals at Buffalo Bills (1:00 p.m. ET)
Kickoff Weather: 57°F, partly cloudy, WSW 17 mph
Cardinals
Inactives:
Lineup notes: No injuries of fantasy relevance.
Bills
Inactives:
Lineup notes: WR Curtis Samuel (toe) practiced fully all week and will play.
Tennessee Titans at Chicago Bears (1:00 p.m. ET)
Kickoff Weather: 68°F, cloudy, W 10 mph
Titans
Inactives:
Lineup notes: WR DeAndre Hopkins (knee) was limited all week and deemed questionable. He’ll be a game-time decision.
Bears
Inactives:
Lineup notes: WR Keenan Allen (heel) practiced fully Friday but remains questionable.
New England Patriots at Cincinnati Bengals (1:00 p.m. ET)
Kickoff Weather: 64°F, clear
Patriots
Inactives:
Lineup notes: WR Kendrick Bourne (knee) remains on the PUP. RB Antonio Gibson (hip) is questionable after limited work Thursday and Friday. TE Hunter Henry (foot) practiced all week and is good to go.
Bengals
Inactives:
Lineup notes: WR Tee Higgins (hamstring) is doubtful after not practicing Friday. WR Ja’Marr Chase (personal, illness) is questionable after he was limited in practice until Friday because of a contract dispute before picking up an “illness” designation on Saturday. He’s a true game-time call. QB Joe Burrow (wrist) practiced all week and will play.
Houston Texans at Indianapolis Colts (1:00 p.m. ET)
Kickoff Weather: 64°F, clear (retractable-roof dome)
Texans
Inactives:
Lineup notes: No injuries of fantasy relevance.
Colts
Inactives:
Lineup notes: WR Josh Downs (ankle) is out for Week 1. PK Spencer Shrader was elevated on Saturday with PK Matt Gay (hernia) deemed questionable.
Jacksonville Jaguars at Miami Dolphins (1:00 p.m. ET)
Kickoff Weather: 87°F, mostly clear
Jaguars
Inactives:
Lineup notes: No injuries of fantasy relevance.
Dolphins
Inactives:
Lineup notes: WR Tyreek Hill (thumb) dealt with a thumb issue in the preseason, but he hasn’t been on the injury report all week. CB Jalen Ramsey (hamstring) is questionable for the opener.
Carolina Panthers at New Orleans Saints (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Panthers
Inactives:
Lineup notes: TE Tommy Tremble (hamstring, back) and TE Ian Thomas (calf), the team’s top-two tight ends were ruled out this week. Thomas has since been placed on IR. RB Miles Sanders (finger) had a full session Friday and is good to go.
Saints
Inactives:
Lineup notes: RB Kendre Miller (hamstring) is on IR and will miss the first four games.
Minnesota Vikings at New York Giants (1:00 p.m. ET)
Kickoff Weather: 64°F, mostly clear
Vikings
Inactives:
Lineup notes: TE T.J. Hockenson (knee) remains on the PUP. WRs Jordan Addison (ankle) and Jalen Nailor (ankle) participated fully Friday and will go.
Giants
Inactives:
Lineup notes: No injuries of fantasy relevance.
Late afternoon
Las Vegas Raiders at Los Angeles Chargers (4:05 p.m. ET)
Kickoff Weather: 102°F, clear, SW 10 mph (open-air dome)
Raiders
Inactives:
Lineup notes: TE Brock Bowers (foot) made it through a full practice Friday and is good to go. Rookie OG Jackson Powers-Johnson (illness) was ruled out for his would-be NFL debut.
Chargers
Inactives:
Lineup notes: WR DJ Chark Jr. (hip) was placed on IR on Saturday. QB Justin Herbert (foot) and WR Joshua Palmer (knee) had minor issues Thursday and Friday, but they practiced fully both days.
Denver Broncos at Seattle Seahawks (4:05 p.m. ET)
Kickoff Weather: 73°F, clear
Broncos
Inactives:
Lineup notes: No injuries of fantasy relevance.
SEahawks
Inactives:
Lineup notes: WR Tyler Lockett (thigh) is questionable, but he had his first full session Friday, suggesting he’s indeed ready to go. TE Noah Fant (toe) did as well, but he carries no injury status.
Dallas Cowboys at Cleveland Browns (4:25 p.m. ET)
Kickoff Weather: 63°F, clear, @ 13 mph
Cowboys
Inactives:
Lineup notes: WR CeeDee Lamb was officially elevated from the exempt list and will play.
Browns
Inactives:
Lineup notes: RB Nick Chubb (knee) remains on the PUP. LT Jedrick Wills (knee) is out, and RT Jack Conklin (knee) is questionable. WR Jerry Jeudy (knee) practiced fully all week and will roll.
Washington Commanders at Tampa Bay Buccaneers (4:25 p.m. ET)
Kickoff Weather: 77°F, 55% chance of light rain
Commanders
Inactives:
Lineup notes: No injuries of fantasy relevance.
Buccaneers
Inactives:
Lineup notes: WR Trey Palmer (concussion) practiced all week but remains questionable.
Sunday Night Football
Los Angeles Rams at Detroit Lions (8:20 p.m. ET)
Kickoff Weather: Dome stadium
Rams
Inactives:
Lineup notes: TE Tyler Higbee (knee) remains on the PUP. RT Rob Havenstein (ankle) is questionable after he saw limited work all week. WR Puka Nacua (knee) practiced fully all week and is good to go.
Lions
Inactives:
Lineup notes: No injuries of fantasy relevance.
Monday Night Football
New York Jets at San Francisco 49ers (8:15 p.m. ET)
Kickoff Weather:78°F, clear, NNW 10 mph
Jets
Lineup notes: WR Mike Williams (knee) practiced fully all week and isn’t on the final report with a designation.
49ers
Lineup notes: RB Elijah Mitchell (hamstring) will spend the season on IR. RB Christian McCaffrey (calf, Achilles) was limited all week and is expected to receive his usual workload, despite being officially questionable.