First look: USC at UCLA odds and lines

Looking at Saturday’s USC Trojans at UCLA Bruins college football odds, lines and trends. Here’s what you need to know.

The No. 6 USC Trojans (9-1, 7-1 Pac-12) and No. 16 UCLA Bruins (8-2, 5-2) clash in an battle Saturday. Kickoff at the Rose Bowl in Pasadena is scheduled for 8 p.m. ET (FOX). Below, we look at USC vs. UCLA from Tipico Sportsbook; check back for all our college football picks and predictions.

USC defeated Colorado Friday. The favored-by-34.5 Trojans outgained the Buffaloes 531 yards to 259 in a 55-17 conquest. Southern Cal — the No. 8 team in last week’s College Football Playoff rankings — has now scored 141 points across 3 straight wins since falling to No. 10 Utah Oct. 15.

The Bruins — tabbed No. 12 by the CFP committee — were 20-point home favorites against Arizona Saturday, but they fell to the Wildcats 34-28. UCLA fell behind 14-0 early only to come back and take a 28-24 lead by the 10:22-mark of the 4th quarter. Arizona then tacked on the final 10 points of the game, and the Bruins fell at the Rose Bowl for the 1st time since Oct. 23, 2021.

Rankings courtesy the AFCA Coaches Poll powered by USA TODAY Sports.

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USC at UCLA odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:30 p.m. ET.

  • Moneyline: Off the board
  • Against the spread (ATS): USC -1.5 (-111) | UCLA +1.5 (-109)
  • Over/Under (O/U): 73.5 (O: -110 | U: -110)

2022 betting stats

  • ML: USC 9-1 | UCLA 8-2
  • ATS: USC 6-4 | UCLA 6-4
  • O/U: USC 7-3 | UCLA 7-3

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USC vs. UCLA head-to-head

Southern Cal and Cal-Los Angeles first met on the gridiron in 1929. USC won the first 2 meetings in shutout fashion, and the Trojans lead the all-time series 49-33-7.

The USC lead includes taking 5 of the last 7 games. But not last year’s (Nov. 20): the Bruins tallied their most points in series history, as they drubbed the Trojans 62-33. Last year’s Over (66.5) cashed easily and has been a winner in 4 straight USC-UCLA games.

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