The Tennessee Titans (0-1) and Buffalo Bills (1-0) head into Week 2 trending in opposite directions after the season opener. They’ll square off next Monday night, the first part of a doubleheader. Kickoff will be at 7:15 p.m. ET (ESPN) from Highmark Stadium in Buffalo. Below, we look at Titans vs. Bills odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
The Titans were stunned by the New York Giants 21-20 at home Sunday. The Giants scored a touchdown with 1:06 left in the game and successfully converted a 2-point conversion to take a 1-point lead. Tennessee was favored by 5.5 points in that game, failing to even win outright against a Giants team that won 4 games last year.
The Bills stomped the defending champions, beating the Los Angeles Rams 31-10 in the season opener on Thursday night. After being tied 10-10 at halftime, the Bills scored 21 unanswered points in the final 30 minutes, sacking QB Matthew Stafford 7 times and picking him off 3 times. Aside from a couple of INTs, QB Josh Allen looked like an MVP favorite.
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Titans at Bills odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2:51 p.m. ET.
- Money line (ML): Titans +360 (bet $100 to win $360) | Bills -500 (bet $500 to win $100)
- Against the spread (ATS): Titans +9.5 (+100) | Bills -9.5 (-120)
- Over/Under (O/U): 49.5 (O: -108 | U: -112)
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2022 betting stats
- ML: Titans 0-1 | Bills 1-0
- ATS: Titans 0-1 | Bills 1-0
- O/U: Titans 0-1 | Bills 0-1
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Titans at Bills head-to-head
The Titans and Bills have met in October in each of the last 4 seasons, splitting those 4 matchups 2-2. The Titans won the last 2 meetings, most recently beating the Bills 34-31 last season as 6-point underdogs. In their last 9 meetings, the Titans are 6-3 SU and 6-3 ATS.
The total has gone Over in 5 of the last 9 meetings, with the Titans scoring 76 total points in the last 2 matchups. This will be their 1st meeting in Buffalo since 2018 when the Bills beat the Titans 13-12.
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