Tampa Bay Buccaneers at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s Tampa Bay Buccaneers at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

The Tampa Bay Buccaneers (10-4) travel to meet the Carolina Panthers (5-9) for a Week 16 game Sunday at Bank of America Stadium. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Buccaneers vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The Buccaneers are coming off a stunning 9-0 loss to the New Orleans Saints at home last Sunday night, although they’re still 4-1 SU/ATS across the past five outings.

The Panthers are in freefall, losing four straight games while also going 0-4 ATS. All four of those games were with QB Cam Newton back under center. The Over has cashed in five in a row for Carolina, with the defense allowing 27 or more points in each of the past four outings.

Buccaneers at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10 a.m. ET.

  • Money line: Buccaneers -550 (bet $550 to win $100) | Panthers +400 (bet $100 to win $400)
  • Against the spread (ATS): Buccaneers -10.5 (+100) | Panthers +10.5 (-120)
  • Over/Under (O/U): 43.5 (O: -108 | U: -112)

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Buccaneers at Panthers key injuries

Buccaneers

  • WR Jaelon Darden (reserve/COVID) out
  • CB Jamel Dean (illness/non-COVID) questionable
  • WR Mike Evans (hamstring) out
  • WR Breshad Perriman (reserve/COVID) questionable
  • LB Jason Pierre-Paul (shoulder) doubtful
  • CB Richard Sherman (Achilles) questionable
  • S Antoine Winfield Jr. (foot) out

Panthers

  • C Pat Elflein (reserve/COVID) out
  • OT Cam Erving (calf) questionable
  • WR DJ Moore (hamstring) questionable

Let’s Make This Interesting

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Buccaneers at Panthers odds, lines, predictions and picks

Prediction

Buccaneers 29, Panthers 13

Money line

The Buccaneers (-550) are furious after getting blanked at home last week by the mediocre Saints, and they’ll likely take out their aggressions on the poor Panthers (+400).

However, PASS, as risking more than five times your return is just too much, especially with Evans joining WR Chris Godwin (knee) and RB Leonard Fournette (hamstring) on the shelf. Returning WR Antonio Brown is the de facto WR1, and he could be rusty after returning from suspension. If the Panthers D can slow TE Rob Gronkowski, they have a puncher’s chance.

Against the spread

The BUCCANEERS -10.5 (+100) are warranted being at least 10 points better than the skidding Panthers +10.5 (-120), although I don’t like all of the injuries on the offensive side of the ball for Tampa. As such, go lightly.

Over/Under

The lean is to the UNDER 43.5 (-112) in this NFC South battle. Again, the Bucs are racked with injuries on offense, but the Panthers defense has still been unable to stop anyone lately. It will be close. A small-unit bet is warranted, but don’t get carried away.

Also see: All Week 16 odds and lines

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