The Sportsbook Wire team is here to help you with your Week 4 NFL picks. Our writers offer up their selections on the money line, spread and Over/Under for every game on the Week 4 slate. Visit SportsbookWire.com for more NFL picks and predictions throughout the season.
We’re down to five undefeated at 3-0 and another five still looking for their first wins at 0-3. The Tampa Bay Buccaneers and Kansas City Chiefs are not in that prestigious first group but they still share the best odds to win Super Bowl LVI in February.
Check out our staff predictions before locking in your Week 4 NFL picks.
Also see: Week 4 odds and lines
NFL Week 4 staff picks
2021-22 ATS standings
Odds provided by Tipico Sportsbook.
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