First look: Southern Miss at Alabama odds and lines

Previewing the Southern Miss at Alabama Week 4 matchup, with college football odds, trends and head-to-head records.

The Southern Miss Golden Eagles (1-2) and Alabama Crimson Tide (3-0) meet Saturday at Bryant-Denny Stadium in Tuscaloosa, Ala. Kickoff is scheduled for 7:30 p.m. ET. Below, we look at the Southern Miss at Alabama odds and lines; check back for our college football picks and predictions.

The Golden Eagles are 0-2 SU/ATS in two games against FBS opponents, averaging just 8.0 PPG in those two outings while allowing 26.0 PPG. The Under has cashed in all three games for USM to date.

The Crimson Tide, No. 1 in the AFCA Coaches Poll powered by USA TODAY Sports, narrowly escaped with a win at Florida over the weekend, 31-29. After a cover and Under result in its opener against Miami, Alabama is 0-2 ATS with a pair of Over results.

Southern Miss at Alabama odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 7:35 a.m. ET.

  • Money line: None at press time
  • Against the spread (ATS): Southern Miss +44.5, -105 (bet $105 to win $100) | Alabama -44.5, -115 (bet $115 to win $100)
  • Over/Under (O/U): 57.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

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2021 betting stats:

  • ML: Southern Miss 1-2 | Alabama 3-0
  • ATS: Southern Miss 1-2 | Alabama 1-2
  • O/U: Southern Miss 0-3 | Alabama 2-1

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Southern Miss at Alabama head-to-head

The Crimson Tide own a 35-6-2 advantage in the all-time series, and Alabama enters on a six-game win streak. The Tide won 49-7 in the most recent meeting in Tuscaloosa Sept. 21, 2019, and they have scored a total of 101 points while allowing just 19 in the past two victories.

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