South Florida at Houston odds, picks and predictions

Analyzing Wednesday’s South Florida at Houston odds and lines, with college basketball expert picks, predictions and best bets.

The South Florida Bulls (7-9, 0-3 American) meet the No. 1 Houston Cougars (16-1, 4-0) Wednesday at Fertitta Center in Houston. Tip-off is scheduled for 8 p.m. ET (ESPN+). Below, we analyze Tipico Sportsbook’s lines around the South Florida vs. Houston odds, and make our expert college basketball picks, predictions and bets.

Rankings courtesy of the USA TODAY Sports Coaches Poll.

The Bulls are on a 3-game skid, all conference losses against Memphis, Temple and Wichita State. The past 2 games were non-covers as a slight favorite. The Over has cashed in 4 of the past 5 games overall and is 10-2 in the past 12 outings.

The top-ranked Cougars are coming off a 72-59 road win against Cincinnati as a 9.5-point favorite Sunday. Houston has won 7 in a row since its only setback against Alabama on Dec. 10, and the Cougars are 5-1 ATS across the past 6 games overall.

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South Florida at Houston odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:43 a.m. ET.

  • Moneyline (ML): Off the board (OTB)
  • Against the spread (ATS): South Florida +22.5 (-115) | Houston -22.5 (-105)
  • Over/Under (O/U): 128.5 (O: -115 | U: -105)

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South Florida at Houston picks and predictions

Prediction

Houston 79, South Florida 53

Moneyline

The money line is OTB at the time of publishing.

However, Houston would be way too heavy of a favorite to provide any value.

PASS.

Against the spread

HOUSTON -22.5 (-105) is the lean in this AAC battle against struggling South Florida.

The Cougars have posted a 5-1 ATS mark over their last 6, and it isn’t so much the offense driving the cover train lately but it’s their tremendous defense. The Cougars rank No. 1 in the nation in scoring defense, yielding just 51.5 PPG, and they are also No. 1 with a 33.2% field-goal percentage and No. 2 with a 23.9% defensive 3-point percentage.

Over/Under

OVER 128.5 (-115) is worth playing but go with a half-unit only.

While the Cougars have a great defense, the Bulls do not. The Over is 10-2 in the past 12 games overall for South Florida and is 4-0 in its last 4 games against teams with a winning overall record.

The Over is 4-1-1 in the past 6 games overall for Houston, although the Under is 20-8-1 in its last 29 home games. Be careful.

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