Seattle Seahawks at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s Seattle Seahawks at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The Seattle Seahawks (7-5) face the Arizona Cardinals (6-6) for the second time in 3 weeks on Sunday, this time on the road. Kickoff from State Farm Stadium is at 4:05 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Seahawks vs. Cardinals odds, and make our expert NFL picks and predictions.

The Seahawks have won 3 straight games, including a 16-6 home win over the Cardinals in Week 12. Last week, they rallied from a 14-point deficit to beat the New York Jets on the road 26-21 as 1.5-point underdogs. The Over (42) cashed in.

The Cardinals have lost 2 in a row since their bye. Last week, they blew a 13-point lead and lost 23-22 to the Minnesota Vikings on the road, covering the 3.5-point spread as underdogs. The Under (45.5) barely cashed in.

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Seahawks at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 6:29 p.m. ET.

  • Moneyline (ML): Seahawks +120 (bet $100 to win $120) | Cardinals -145 (bet $145 to win $100)
  • Against the spread (ATS): Seahawks +2.5 (-105) | Cardinals -2.5 (-115)
  • Over/Under (O/U): 44.5 (O: -110 | U: -110)

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Seahawks at Cardinals key injuries

Seahawks

  • Michael Dickson (back) questionable
  • OL Stone Forsyth (hand) out
  • RB Kenneth Walker (ankle, calf) questionable

Cardinals

  • CB Elijah Jones (ankle) out
  • DL Naquan Jones (elbow) questionable
  • DL Dante Stills (back) questionable

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Seahawks at Cardinals picks and predictions

Prediction

Cardinals 29, Seahawks 20

Moneyline

The Cardinals have not allowed a TD in their last 3 home games. They have not allowed an opponent to reach 300 yards of offense in 4 straight games.

After only scoring 6 points against Seattle, the Cardinals bounced back to get to the red zone 6 times against Minnesota and gained 406 total yards on a top-10 defense.

Arizona’s offense will bounce back, while the defense will continue to limit Seattle on offense, who hasn’t reached 300 yards of offense during its win streak.

But the spread will be the better bet at -115.

PASS. 

Against the spread

The Seahawks have not covered the spread in a loss this season while the Cardinals have covered the spread in every win this season.

BET CARDINALS -2.5 (-115).

Over/Under

The last 3 meetings between the teams have seen the Under hit. But 3 of the last 4 meetings in Arizona have had totals in the 50s or higher.

BET OVER 44.5 (-110).

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Seattle Seahawks at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s Seattle Seahawks at Arizona Cardinals odds and lines, with expert NFL picks, predictions and best bets.

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The NFC West-leading Seattle Seahawks (5-3) are on the road in Week 9 for a division game against the Arizona Cardinals (3-5). Kickoff at State Farm Stadium in Glendale is at 4:05 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Seahawks vs. Cardinals odds, and make our expert NFL picks and predictions.

The Seahawks have won 3 straight games and 4 of 5 to lead the NFC West at 5-3. As 3-point home favorites last week aganst the New York Giants, they won 27-13 behind QB Geno Smith’s 2 TD passes and a defense that allowed only 225 yards and forced 2 turnovers.

The Cardinals turned the ball over 3 times in the 2nd half of their 34-26 road loss to the Minnesota Vikings in Week 8, failing to cover the 4-point spread. They are last in the NFC West and have not won consecutive games this season. They lost 19-9 to the Seahawks in Week 6 on the road.

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Seahawks at Cardinals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:24 p.m. ET.

  • Moneyline (ML): Seahawks +110 (bet $100 to win $110) | Cardinals -130 (bet $130 to win $100)
  • Against the spread (ATS): Seahawks +2.5 (-110) | Cardinals -2.5 (-110)
  • Over/Under (O/U): 49 (O: -108 | U: -112)

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Seahawks at Cardinals key injuries

Seahawks

  • Corey Blount (quad) questionable
  • WR Marquise Goodwin (groin) out
  • WR Penny Hart (hamstring) questionable
  • LB Darrell Taylor (groin) out

Cardinals

  • Budda Baker (ankle) questionable
  • RB James Conner (ribs) questionable
  • LB Dennis Gardeck (ankle) questionable
  • OL Rodney Hudson (knee) out
  • OL D.J. Humphries (back) questionable

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Seahawks at Cardinals picks and predictions

Prediction

Cardinals 23, Seahawks 20

Moneyline

The Cardinals and Seahawks have split their season series every year since 2019.

This game is essentially a must-win game for Arizona as a loss would drop them 3 games behind Seattle, give the Seahawks a head-to-head tiebreaker and drop Arizona to 0-3 in the division.

The Cardinals have finally started scoring points, averaging 34 points the last 2 weeks, but they also have allowed 34 points each of the last 2 weeks. The return of WR DeAndre Hopkins has jump-started the offense.

They held tough in the Week 6 loss to Seattle, but did not score an offensive touchdown.

The Seahawks, after allowing 34.5 points per game from Weeks 2-5, have allowed 15 per game in their 3-game winning streak.

The Seahawks are playing better overall but the Cardinals find themselves in a desperate situation, which often changes outcomes.

I LEAN CARDINALS (-130).

Against the spread

The Seahawks are 5-3 ATS this season while the Cardinals are 4-4 ATS.

The Seahawks have failed to cover the spread in their last 4 games in November and are 1-9 ATS in their last 10 games following a game in which they had fewer than 90 rushing yards. They had 87 last week against the Giants.

The Cardinals gave up 173 yards on the ground last week to the Vikings and are 5-1 ATS in their last 6 games following a contest allowing 150 or more rushing yards. However, they have failed to cover the spread in their last 5 NFC West games.

Again, desperation is the reason for this pick.

I LEAN CARDINALS -2.5 (-110).

Over/Under

The 2 teams combined for only 28 points in Week 6.

Half of Seattle’s games have had totals of fewer than 49 points. So have half of the Cardinal’s games.

BET UNDER 49 (-112).

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