Seattle Seahawks at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s Seattle Seahawks at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The Seattle Seahawks (7-5) face the Arizona Cardinals (6-6) for the second time in 3 weeks on Sunday, this time on the road. Kickoff from State Farm Stadium is at 4:05 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Seahawks vs. Cardinals odds, and make our expert NFL picks and predictions.

The Seahawks have won 3 straight games, including a 16-6 home win over the Cardinals in Week 12. Last week, they rallied from a 14-point deficit to beat the New York Jets on the road 26-21 as 1.5-point underdogs. The Over (42) cashed in.

The Cardinals have lost 2 in a row since their bye. Last week, they blew a 13-point lead and lost 23-22 to the Minnesota Vikings on the road, covering the 3.5-point spread as underdogs. The Under (45.5) barely cashed in.

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Seahawks at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 6:29 p.m. ET.

  • Moneyline (ML): Seahawks +120 (bet $100 to win $120) | Cardinals -145 (bet $145 to win $100)
  • Against the spread (ATS): Seahawks +2.5 (-105) | Cardinals -2.5 (-115)
  • Over/Under (O/U): 44.5 (O: -110 | U: -110)

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Seahawks at Cardinals key injuries

Seahawks

  • Michael Dickson (back) questionable
  • OL Stone Forsyth (hand) out
  • RB Kenneth Walker (ankle, calf) questionable

Cardinals

  • CB Elijah Jones (ankle) out
  • DL Naquan Jones (elbow) questionable
  • DL Dante Stills (back) questionable

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Seahawks at Cardinals picks and predictions

Prediction

Cardinals 29, Seahawks 20

Moneyline

The Cardinals have not allowed a TD in their last 3 home games. They have not allowed an opponent to reach 300 yards of offense in 4 straight games.

After only scoring 6 points against Seattle, the Cardinals bounced back to get to the red zone 6 times against Minnesota and gained 406 total yards on a top-10 defense.

Arizona’s offense will bounce back, while the defense will continue to limit Seattle on offense, who hasn’t reached 300 yards of offense during its win streak.

But the spread will be the better bet at -115.

PASS. 

Against the spread

The Seahawks have not covered the spread in a loss this season while the Cardinals have covered the spread in every win this season.

BET CARDINALS -2.5 (-115).

Over/Under

The last 3 meetings between the teams have seen the Under hit. But 3 of the last 4 meetings in Arizona have had totals in the 50s or higher.

BET OVER 44.5 (-110).

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Seattle Seahawks at Arizona Cardinals odds, picks and prediction

Analyzing Sunday’s Seattle Seahawks at Arizona Cardinals odds and lines, with expert NFL picks, predictions and best bets.

The Seattle Seahawks (6-10) wrap up their 2021 season on the road against the Arizona Cardinals (11-5) in Week 18. Kickoff is 4:25 p.m. ET at State Farm Stadium. Below, we look at the Seahawks vs. Cardinals odds and lines, and make our best NFL picks, predictions and bets.

The Seahawks failed to qualify for the postseason for just the second time, and have a losing season for the first time, in QB Russell Wilson‘s career. It also marks the first time that they’ve lost 10 games with Pete Carroll as head coach. However, they are coming off a 51-29 home victory in Week 17 over the Detroit Lions.

The Cardinals are going to the postseason for the first time since 2015 and are in contention for the NFC West title. They snapped a three-game losing skid in Week 17 with a 25-22 win over the Dallas Cowboys.

Seahawks at Cardinals odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:27 a.m. ET.

  • Money line: Seahawks +190 (bet $100 to win $190) | Cardinals -240 (bet $240 to win $100)
  • Against the spread (ATS): Seahawks +5.5 (-112) | Cardinals -5.5 (-108)
  • Over/Under (O/U): 47.5 (O: -115 | U: -105)

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Seahawks at Cardinals key injuries

Seahawks

  • Brandon Shell (shoulder, illness) out
  • LB Bobby Wagner (knee) out
  • LB Carlos Dunlap (ankle) questionable
  • TE Will Dissly (heel) questionable
  • Gabe Jackson (knee, illness) questionable

Cardinals

  • RB Chase Edmonds (ribs, toe) out
  • WR Rondale Moore (ankle) out
  • DL Jordan Phillips (knee) out
  • CB Marco Wilson (shoulder) out
  • DL Zach Allen (ankle) questionable
  • RB James Conner (heel) questionable

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Seahawks at Cardinals odds, lines, predictions and picks

Prediction

Cardinals 27, Seahawks 16

Money line

The Seahawks have only lost twice to the Cardinals in State Farm Stadium since Wilson’s career started. The Cardinals are 3-4 at home this season and Seattle is 3-5 away from home. Seattle has lost two of its last three games and allowed 23 to the Cardinals in Week 9 — but it could have been 30 if Matt Prater had not missed an extra point and two field goals.

The Cardinals got their offense back on track last week and are playing for a division title. While a few players are out for the Cards, Seattle will struggle to make plays without Wagner in the middle of the defense.

Take the CARDINALS (-240).

Against the spread

The Seahawks are 8-8 ATS on the season but failed to cover the spread in their game against the Cardinals in Seattle.

The Cardinals are 10-6 ATS this season. They have the defense playing well and the offense back on track.

The Cardinals have covered the spread in all but one of their victories this season.

Take the CARDINALS -5.5 (-108).

Over/Under

Four of the Seahawks’ last five games have gone Over the projected total but only one other game all year has.

The last three games for the Cardinals stayed Under the projected total and their game in Seattle went Under.

Take UNDER 47.5 (-105).

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Seattle Seahawks at Arizona Cardinals odds, picks and prediction

Previewing the Seattle Seahawks and Arizona Cardinals Week 7 betting odds and lines, with NFL betting picks, tips and predictions.

The Arizona Cardinals (4-2) return home after three straight road games to take on the undefeated Seattle Seahawks (5-0). The clash between the top two teams in the NFC West kicks off at State Farm Stadium at 8:20 p.m. ET Sunday of Week 7. Below, we preview the Seahawks-Cardinals Week 7 betting odds and lines and make our NFL picks and predictions.

Seahawks at Cardinals betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday 10:50 a.m. ET.

  • Money line: Seahawks -189 (bet $189, win $100) | Cardinals +160 (bet $100, win $160)
  • Against the spread/ATS: Seahawks -3.5 (-106) | Cardinals +3.5 (-115)
  • Over/Under: 55.5 (O: -110, U: -110)

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Seahawks at Cardinals game notes

  • Seahawks QB Russell Wilson leads the NFL with 19 touchdown passes.
  • Seattle has the league’s No. 1 scoring offense in the league at 33.8 points per game.
  • The Cardinals defense allows the second-fewest points per game at 18.7.
  • The Cardinals have one of the best rushing attacks in the league, as they are No. 1 in yards per carry and No. 1 in rushing touchdowns.
  • Cardinals QB Kyler Murray has 16 combined touchdowns (rushing and passing).

Seahawks at Cardinals key injuries

Seahawks

  • Jamal Adams (groin) doubtful
  • RB Carlos Hyde (shoulder) questionable
  • Mike Iupati (back) questionable

Cardinals

  • WR DeAndre Hopkins (ankle) questionable
  • CB Dre Kirkpatrick (foot) questionable
  • OL Kelvin Beachum (ankle) questionable

Seahawks at Cardinals: Odds, betting lines, picks and prediction

Prediction

Cardinals 27, Seahawks 24

Money line (?)

The Cardinals are playing defense at a high level but the Seahawks seem to be able to come back from any deficit. The Cardinals have not beaten the Seahawks at home since 2012, but Seattle allow over 470 yards of offense per game and the Cardinals have weapons to put up points. This is the game where the Seahawks can fall. Take the CARDINALS (+160).

Against the spread (?)

Seattle is 4-1 ATS this season and the Cardinals are 4-2 ATS. The Cardinals are 2-0 ATS as an underdog. Take the CARDINALS +3.5 (-115).

Over/Under (?)

Despite the talk of the Cardinals offense, it is the defense that has mattered most. All six of Arizona’s games have gone Under the total. Seattle is 3-2 O/U. While many expect a shootout, both team’s defenses will make it an entertaining game, but it will fall short of the total. Take UNDER 55.5 (-110).

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