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The NFC West-leading Seattle Seahawks (5-3) are on the road in Week 9 for a division game against the Arizona Cardinals (3-5). Kickoff at State Farm Stadium in Glendale is at 4:05 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Seahawks vs. Cardinals odds, and make our expert NFL picks and predictions.
The Seahawks have won 3 straight games and 4 of 5 to lead the NFC West at 5-3. As 3-point home favorites last week aganst the New York Giants, they won 27-13 behind QB Geno Smith’s 2 TD passes and a defense that allowed only 225 yards and forced 2 turnovers.
The Cardinals turned the ball over 3 times in the 2nd half of their 34-26 road loss to the Minnesota Vikings in Week 8, failing to cover the 4-point spread. They are last in the NFC West and have not won consecutive games this season. They lost 19-9 to the Seahawks in Week 6 on the road.
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Seahawks at Cardinals odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:24 p.m. ET.
- Moneyline (ML): Seahawks +110 (bet $100 to win $110) | Cardinals -130 (bet $130 to win $100)
- Against the spread (ATS): Seahawks +2.5 (-110) | Cardinals -2.5 (-110)
- Over/Under (O/U): 49 (O: -108 | U: -112)
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Seahawks at Cardinals key injuries
Seahawks
- S Corey Blount (quad) questionable
- WR Marquise Goodwin (groin) out
- WR Penny Hart (hamstring) questionable
- LB Darrell Taylor (groin) out
Cardinals
- S Budda Baker (ankle) questionable
- RB James Conner (ribs) questionable
- LB Dennis Gardeck (ankle) questionable
- OL Rodney Hudson (knee) out
- OL D.J. Humphries (back) questionable
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Seahawks at Cardinals picks and predictions
Prediction
Cardinals 23, Seahawks 20
Moneyline
The Cardinals and Seahawks have split their season series every year since 2019.
This game is essentially a must-win game for Arizona as a loss would drop them 3 games behind Seattle, give the Seahawks a head-to-head tiebreaker and drop Arizona to 0-3 in the division.
The Cardinals have finally started scoring points, averaging 34 points the last 2 weeks, but they also have allowed 34 points each of the last 2 weeks. The return of WR DeAndre Hopkins has jump-started the offense.
They held tough in the Week 6 loss to Seattle, but did not score an offensive touchdown.
The Seahawks, after allowing 34.5 points per game from Weeks 2-5, have allowed 15 per game in their 3-game winning streak.
The Seahawks are playing better overall but the Cardinals find themselves in a desperate situation, which often changes outcomes.
I LEAN CARDINALS (-130).
Against the spread
The Seahawks are 5-3 ATS this season while the Cardinals are 4-4 ATS.
The Seahawks have failed to cover the spread in their last 4 games in November and are 1-9 ATS in their last 10 games following a game in which they had fewer than 90 rushing yards. They had 87 last week against the Giants.
The Cardinals gave up 173 yards on the ground last week to the Vikings and are 5-1 ATS in their last 6 games following a contest allowing 150 or more rushing yards. However, they have failed to cover the spread in their last 5 NFC West games.
Again, desperation is the reason for this pick.
I LEAN CARDINALS -2.5 (-110).
Over/Under
The 2 teams combined for only 28 points in Week 6.
Half of Seattle’s games have had totals of fewer than 49 points. So have half of the Cardinal’s games.
BET UNDER 49 (-112).
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