San Francisco 49ers vs New Orleans Saints Prediction, Game Preview

San Francisco 49ers vs New Orleans Saints prediction, game preview, and fantasy player to watch.

San Francisco 49ers vs New Orleans Saints prediction, game preview, and fantasy player to watch.


San Francisco 49ers vs New Orleans Saints Broadcast

Date: Sunday, November 15
Game Time: 4:25 ET
Venue: Mercedes-Benz Stadium, New Orleans, LA
Network: FOX

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All of the CFN Fearless Predictions

San Francisco 49ers (4-5) vs New Orleans Saints (6-2) Game Preview

For latest lines and to bet on the NFL, go to BetMGM


Why San Francisco 49ers Will Win

The passing game still works.

It might not have a big downfield offense, and it’s missing some key parts – the entire team is – but even with Nick Mullens taking over the quarterbacking reins, the O is still getting well over 250 yards per game through the air.

Combine that with a ground game that’s doing just enough to close – the team leads the NFL in touchdown runs and has only allowed five scores – but …

Why New Orleans Saints Will Win

New Orleans isn’t giving up a thing on the ground.

Eight yards. That’s how many Tampa Bay was able to gain last week against a Saint D that came up with one of the season’s most dominant performances.

The Saint offense was able to spread the ball around well, the offense put up 420 yards without getting Michael Thomas involved all that much. On both sides of the ball, the pressure will keep coming.

Fantasy Football Player To Watch

RB Latavius Murray, New Orleans
New Orleans won’t want to get quirky here. It’ll want to control the ball on offense and grind-it-out with short passes and a heavy dose of Murray. Although he’s end-zone dependent for his big weeks, keep in mind that he received more carries than Alvin Kamara last week against the Bucs. Here comes the end to the scoring slump.

What’s Going To Happen

New Orleans won’t be able to repeat the brilliance of Sunday night against the Bucs, but it’ll be workmanlike and sound on both sides of the ball – helped by being +2 in turnover margin – to push through.

CFN Experts Picks: NFL

San Francisco 49ers vs New Orleans Saints Prediction, Line

New Orleans 35, San Francisco 24
Bet on 49ers vs Saints with BetMGM
New Orleans -10, o/u: 49
ATS Confidence out of 5: 2

Must See Rating: 2.5

5: Alex Trebek
1: “Who are three people who have never been in my kitchen.”

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San Francisco 49ers at New Orleans Saints odds, picks and best bets

Previewing Sunday’s San Francisco 49ers at New Orleans Saints sports betting odds and lines, with Week 14 NFL betting picks and best bets.

The San Francisco 49ers (10-2) visit the New Orleans Saints (10-2) Sunday at Mercedes-Benz Superdome in a marquee NFC matchup between teams battling for a playoff bye. The game will kick off at 1 p.m. ET. We analyze the 49ers-Saints odds and sports betting lines, while providing sports betting tips and advice on this matchup.

49ers at Saints: Week 14 preview, betting trends and notes


Get some action on the games by betting at BetMGM. New customer offer: RISK-FREE First Bet (up to $500!) paid in free bets.


  • The Saints are coming off a 26-18 road win over the Atlanta Falcons on Thanksgiving. The 49ers took their second loss of the season on the road, losing 20-17 at the Baltimore Ravens.
  • This is the first meeting between the two teams since Kyle Shanahan was hired as 49ers head coach to begin the 2017 season.
  • The 49ers have had three different leading rushers and four different leading receivers this season. The Saints have had two different rushing leaders and three receiving leaders.
  • The 49ers are 4-19 when allowing 250 or more passing yards in a game since the start of 2016. Saints QB Drew Brees is averaging 255.8 passing yards per game this year. The Niners are allowing a league-low 134.3 yards per game through the air.
  • The Saints are tied for second in the league with a turnover differential of plus-11. The Niners are eighth at plus-6.

49ers at Saints: Key injuries

49ers RB Matt Breida (ankle) is expected to return this week.

49ers at Saints: Odds, betting lines and prediction

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 8 p.m. ET.

Prediction

49ers 23, Saints 18

Moneyline (?)

The 49ers (+120) have the defense to slow Brees and RB Alvin Kamara. They’re in a tight battle with the Seattle Seahawks for the NFC West title, while the Saints have cruised all season atop the NFC South.

The Niners have more offensive weapons as head coaches Shanahan and Sean Payton meet in a play-calling battle.

Against the Spread (?)

The NINERS (+2.5, -106) are also a good play on the spread where they’ll need to stay within two points in a loss or win outright. The Saints are 8-4 against the spread overall while the 49ers are 7-4-1, but San Francisco covers by an average of 10.1 points per game with New Orleans covering by an average of just 0.7 PPG.

Over/Under (?)

Take the UNDER 44.5 (-106) as the Niners try to slow this one down. Both teams play more than a point below the projected point totals on average with the Saints 6-6 against the Over/Under and the 49ers 5-7. Games at the Superdome have gone 3-3 against the O/U.

Want action on this game? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com.

Esten’s NFL betting record: 34-40

Follow @EstenMcLaren and @SportsbookWire on Twitter.

Gannett may earn revenue from audience referrals to betting services.  Newsrooms are independent of this relationship and there is no influence on news coverage.

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