Dallas Cowboys home underdogs vs. San Francisco 49ers in Week 15

The San Francisco 49ers are betting favorites in their Week 15 road matchup with the Dallas Cowboys.

The San Francisco 49ers (5-8) are on the road and take on the Dallas Cowboys (4-9) in a battle of two last-place teams in Week 15. Kickoff is at 1 p.m. ET at AT&T Stadium in Arlington, Texas. Below, we take a look at the early 49ers-Cowboys Week 15 betting odds and lines at BetMGM Sportsbook.

San Francisco is coming off its second straight loss and fifth in six games. The 49ers were fantastic defensively in a 23-15 Week 14 loss to the Washington Football Team, allowing only 193 total yards of offense and taking the ball away three times; however, the offense turned it over three times as well and had an interception and a fumble each returned for touchdowns. The 49ers were eliminated from NFC West contention.

The Cowboys beat the Cincinnati Bengals 30-7 Sunday. QB Andy Dalton threw 2 touchdown passes against his former team and the defense forced three turnovers, returning a fumble for a touchdown.

49ers at Cowboys betting odds, spread and line

Odds via BetMGM; last updated Monday at 1:25 p.m. ET. 

  • Money line: 49ers -125 (bet $125 to win $100) / Cowboys +105 (bet $100 to win $105) | Bet now
  • Against the spread: 49ers -1.5, -110 (bet $110 to win $100) / Cowboys +1.5, -110 (bet $110 to win $100) | Bet now
  • Total: 44.5, Over -115 (bet $115 to win $100) / Under -105 (bet $105 to win $100) | Bet now

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The 49ers, at -125 odds, have an implied 55.56% chance of winning, or 4/5 fractional odds. If San Francisco wins by more than 1 point, a 49ers -1.5 (-110) bet wins.

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At +105 odds, the Cowboys have an implied 48.78% chance of beating the 49ers or 21/20 fractional odds. Dallas must win outright, tie or lose by only one point for a Cowboys +1.5 (-110) ATS ticket to cash.

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