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Cincinnati Reds at Chicago White Sox odds, picks and prediction

Analyzing Wednesday’s Cincinnati Reds at Chicago White Sox odds and lines, with MLB picks and predictions.

The Cincinnati Reds (82-76) and Chicago White Sox (90-68) conclude a two-game interleague set Wednesday. First pitch is set for 8:10 p.m. ET at Guaranteed Rate Field. Let’s analyze the lines around the Reds vs. White Sox odds with MLB picks and predictions.

RHP Sonny Gray is the scheduled starting pitcher for the Reds. Gray is 7-8 with a 3.99 ERA, 1.21 WHIP, 10.3 K/9, and 3.3 BB/9 over 130 2/3 IP across 25 starts.

  • Walked 4 batters and allowed 4 ER through 4 IP in his last start. Has allowed 8 runs (7 earned) in his last 10 IP after logging a 1.80 ERA from Aug. 20-Sept. 12.
  • Owns a 2.97 ERA and 1.12 WHIP through 11 road starts.

LHP Carlos Rodon is the scheduled starter for the White Sox. He is 12-5 with a 2.47 ERA, 0.97 WHIP, 12.8 K/9, and 2.4 BB/9 in 127 2/3 IP over 23 starts.

  • Has been battling shoulder soreness and makes this start on eight days of rest. When pitching on six or more days of rest, Rodon has held opposing batters to a .502 OPS this season and a .674 mark over his career (career .708 OPS allowed overall).
  • Facing a Reds offense which went into this series ranked 27th in MLB in OPS vs. left-handed pitching (.691 OPS) and third in the league in OPS vs. right-handed pitching (.788 OPS).

Reds at White Sox odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 3:50 p.m. ET.

  • Money line: Reds +145 (bet $100 to win $145) | White Sox -180 (bet $180 to win $100)
  • Against the spread/ATS: Reds +1.5 (-150) | White Sox -1.5 (+122)
  • Over/Under: 7.5 (O: -112 | U: -108)

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Prediction

Reds 4, White Sox 3

Money line (ML)

Cincinnati had a four-game win streak snapped when it dropped Tuesday’s series opener 7-1. The Reds’ 1 run on 4 hits is part of a larger trend. Cincy has clocked a mere .594 OPS over its last 16 road games.

The White Sox have won three straight. They are 11-5 over their last 16 at home and own a high-contact .857 OPS over those games.

Gray of late has not been the same pitcher that was missing a lot of bats while stringing together big performances midsummer. However, current Pale Hose batters own a mere .456 OPS against him, and the Rodon shoulder situation tilts things toward the visiting nine.

BACK CINCINNATI (+145).

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Run line/Against the spread (ATS)

The Reds are a lean in principle, but the pricing here nixes any value. PASS.

Over/Under (O/U)

The weather for this one makes for a cool night with a light pitcher’s breeze in from left center field. Adding in the starters and two likable-of-late bullpens tilts us toward enough of a chance of a 5- or 6-run game.

TAKE THE UNDER 7.5 (-108).

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Cincinnati Reds at Chicago White Sox odds, picks and prediction

Analyzing Tuesday’s Cincinnati Reds at Chicago White Sox odds and lines, with MLB expert picks and predictions.

The Chicago White Sox (89-68) host the Cincinnati Reds (82-75) Tuesday to begin a two-game interleague miniseries at Guaranteed Rate Field. First pitch is scheduled for 8:10 p.m. ET. Let’s analyze the lines around the Reds vs. White Sox odds with MLB picks and predictions.

Cincy has rattled off four straight wins but needs an absolute collapse from the St. Louis Cardinals, who are 5.5 games ahead of the Reds for the second NL Wild Card seed. The Cardinals clinch that spot with one victory.

Chicago has clinched the AL Central and is pretty much locked into the 2- vs. 3-seed American League Division Series matchup vs. whoever comes out of the AL West. The White Sox have been playing .500 baseball over their past 10 and 20 games.

Season series: Tied 1-1.

RHP Riley O’Brien makes his MLB debut for the Reds. O’Brien was 7-7 with a 4.55 ERA (112 2/3 IP, 57 ER), 1.31 WHIP, 4.4 BB/9 and 9.7 K/9 over 22 starts and one relief appearance in Triple-A this season. He is the 24th-ranked prospect in Cincinnati’s farm system.

RHP Reynaldo Lopez is Chicago’s projected starter. Lopez is 3-3 with a 3.16 ERA (51 1/3 IP, 18 ER), 0.96 WHIP, 2.1 BB/9 and 8.9 K/9 over eight starts and 10 bullpen outings.

  • Last outing: No-decision with 3 1/3 IP, 2 ER, 4 H, 0 BB and 4 K in Chicago’s 7-2 victory at the Cleveland Indians Thursday.
  • 2021 home splits: 2-1 with a 3.00 ERA (24 IP, 8 ER), 0.79 WHIP and 5.2 K/BB in three starts and five relief appearances.

Reds at White Sox odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 1:35 p.m. ET.

  • Money line: Reds +155 (bet $155 to win $100) | White Sox -190 (bet $190 to win $100)
  • Against the spread/ATS: Reds +1.5 (-130) | White Sox -1.5 (+105)
  • Over/Under: 9.5 (O: +110 | U: -135)

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Prediction

White Sox 6, Reds 2

Money line (ML)

“LEAN” to the WHITE SOX (-190) for a half unit since this is on the fringe of my price range considering Lopez isn’t a “top of the rotation” starter on Chicago’s pitching staff.

Also, perhaps O’Brien gives Cincy a decent outing because no one in this White Sox lineup has faced O’Brien in the majors yet.

However, Chicago is six games above-.500 in interleague games, 12 games above-.500 vs. righty starters and 22 games above-.500 at home.

Plus I’m skeptical of Cincy’s motivation since it’s all but eliminated from playoff contention and whose starter is making their debut in “The Show”.

Furthermore, the White Sox has edges in the three most important phases of the game: Starting and relief pitching and hitting.

Lastly, we have “sharp line movement” towards Chicago since this game opened with the White Sox being around -163 as a consensus favorite before being steamed up by the market to the current price.

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Run line/Against the spread (ATS)

PASS because we don’t really know what we’re going to see from O’Brien today, Cincy’s bullpen is the only unit that’s pitching better than Chicago’s this month, and the Reds are 31-15 ATS as a road underdog.

Over/Under (O/U)

“LEAN” to the UNDER 9.5 (-135) because of the “reverse line movement” in the betting market, and the oddsmakers trying to steer bettors away from the Over by making the Under so expensive.

For instance, according to Pregame.com, roughly 70% of the cash and around two-thirds of the bets placed are on the Over, but this total is heading south. It’s a red flag in sports betting whenever the House makes the more popular side cheaper.

For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow Geoff Clark on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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