First look: Las Vegas Raiders at Buffalo Bills odds and lines

Looking at Sunday’s Las Vegas Raiders at Buffalo Bills Week 2 NFL odds, lines and trends. Here’s what you need to know.

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The Las Vegas Raiders (1-0) visit the Buffalo Bills (0-1) Sunday in Week 2. Kickoff from Highmark Stadium is set for 1 p.m. ET (CBS). Below, we look at Raiders vs. Bills odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

Las Vegas came away with a 17-16 road win as a 3-point underdog in an AFC West battle at the Denver Broncos in Week 1. Two of the newest Raiders — through free agency — came up big as QB Jimmy Garoppolo connected with WR Jakobi Meyers on a 6-yard pass for the go-ahead and eventual winning TD with 6:34 to go. Garoppolo finished with 200 passing yards, 2 touchdowns and 1 pick, while Meyers finished with a game-high 9 catches for 81 yards and 2 TDs. Neither team could really get much going thanks to some stellar defense and a lot of penalties.

Buffalo suffered a 22-16 OT loss as a 2.5-point road favorite at the hands of the New York Jets Monday. QB Josh Allen struggled, losing a fumble and throwing 3 interceptions. He completed 71% (29 of 41) of his passes for 236 yards and 1 TD. WR Stefon Diggs finished with 102 receiving yards on 10 catches — both game-highs — and 1 score.

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Raiders at Bills odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 3:52 a.m. ET.

  • Moneyline (ML): Raiders +320 (bet $100 to win $320) | Bills -405 (bet $405 to win $100)
  • Against the spread (ATS): Raiders +8.5 (-105) | Bills -8.5 (-115)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Raiders 1-0 | Bills 0-1
  • ATS: Raiders 1-0 | Bills 0-1
  • O/U: Raiders 0-1 | Bills 0-1

Raiders vs. Bills head-to-head

The all-time series is tied 21-21.

The Bills took the last 2 meetings, including the most recent tilt 30-23 as 3-point home favorites Oct. 4, 2020 — the Over/Under pushed at 53.

The Raiders last win in the series was 38-24 victory — also as 3-point home favorites — Dec. 4, 2016.

The Bills are 4-2 in the last 6 meetings, including 3-0 at home.

The Raiders’ last win in Buffalo came in 2002, a 49-31 victory as 3-point favorites.

The Over has hit 7 games in a row in the series and is 8-2 in the last 10 meetings.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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