Ole Miss at LSU odds, picks and predictions

Analyzing Saturday’s Ole Miss at LSU odds and lines, with college football expert picks, predictions and best bets.

The No. 7 Ole Miss Rebels (7-0, 3-0 SEC) square off against the LSU Tigers (5-2, 3-1) Saturday at Tiger Stadium. Kickoff is scheduled for 3:30 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Ole Miss vs. LSU odds, and make our expert college football picks and predictions.

The Rebels are among the 3 unbeaten teams in the SEC after defeating Auburn 48-34 last Saturday. Ole Miss has gotten stellar production on the ground from RB Quinshon Judkins and RB Zach Evans this season with a combined 1,325 rushing yards and 17 rushing touchdowns from the duo.

The Tigers are coming off a 45-35 comeback win over Florida last Saturday following a 40-13 loss to then-No.8 Tennessee 2 weeks ago. QB Jayden Daniels is the engine for LSU’s offense as he’s thrown for 1,564 yards and 10 touchdowns while also adding 403 rushing yards and 6 rushing touchdowns.

Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.

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Ole Miss at LSU odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:46 a.m. ET.

  • Moneyline (ML): Ole Miss +110 (bet $100 to win $110) | LSU -135 (bet $135 to win $100)
  • Against the spread (ATS): Ole Miss +2.5 (-112) | LSU -2.5 (-108)
  • Over/Under (O/U): 67.5 (O: -110 | U: -110)

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Ole Miss at LSU picks and predictions

Prediction

Ole Miss 31, LSU 24

Moneyline

Give me OLE MISS (+110) at plus money despite being the superior team. While some could be concerned with the Tigers playing at home, the Rebels should have success running the ball and controlling the time of possession in this game.

Against the spread

Considering that I have the Rebels improving to 8-0 on the season, OLE MISS +2.5 (-112) is where I’m going in this contest. Even if the Rebels aren’t able to come away with a win, they’re capable of keeping this game within 2 points.

Over/Under

UNDER 67.5 (-110) is the move in this game as Ole Miss and LSU could try to control the clock more with it being a crucial SEC matchup. These 2 teams are a combined 5-9 to the Over this season.

The Rebels have gone Under in 9 of their last 10 games against a team with a winning record. Meanwhile, the Tigers are 7-1 to the Under in their last 8 games following an ATS win and are 4-1 to the Under in their last 5 games overall.

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First look: Ole Miss at LSU odds and lines

Looking at Saturday’s Ole Miss at LSU college football odds, lines and trends. Here’s what you need to know.

The LSU Tigers (5-2, SEC 3-1) welcome the No. 7 Ole Miss Rebels (7-0, 3-0) to Tiger Stadium Saturday. Kickoff is set for 3:30 p.m. ET (CBS). Below, we look at Ole Miss vs. LSU odds from Tipico Sportsbook; check back for all our college football picks and predictions.

LSU, the first team outside of the AFCA Coaches Poll, is coming off a 45-35 win over Florida. The week prior, it was destroyed by Tennessee 40-13. LSU also has a key win over Mississippi State this season.

The Tigers are led by coach Brian Kelly, who is in his first season in Baton Rouge, leading Notre Dame for the 12 prior. LSU’s main weapon is QB Jayden Daniels, who leads the team in both passing and rushing yards.

Ole Miss is led by QB Jaxson Dart, who is 12 yards shy of 1,500 on the season. The Rebels also have a pair of running backs that each have over 600 yards on the ground.

Ole Miss is No. 7 in the AFCA Coaches Poll powered by USA TODAY Sports. Its key win this season was a 22-19 home victory over the top-25 Kentucky Wildcats.

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Ole Miss at LSU odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 2:20 p.m. ET.

  • Moneyline (ML): Off the board.
  • Against the spread (ATS): Ole Miss +1.5 (-107) | LSU -1.5 (-115)
  • Over/Under (O/U): 66.5 (O: -108 | U: -112)

2022 betting stats

  • ML: Ole Miss 7-0 | LSU 5-2
  • ATS: Ole Miss 3-4 | LSU 4-3
  • O/U: Ole Miss 3-4 | LSU 2-5

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Ole Miss vs. LSU head-to-head

Both Ole Miss and LSU joined the SEC in its inaugural season almost a century ago, founded in 1932.

Ole Miss won at home last season, but that is as far as its success has gone. Before 2021, LSU won the previous 5 matchups. LSU also has 23 more wins in the series and an overall 64-41-4 record.

LSU has both a top-50 offense and defense of the 131 FBS programs, scoring 33.7 points per game and allowing just 21.3. Ole Miss can impressively top that with a top-16 offense and defensive, scoring 40.9 per game and allowing 17.3.

Play our free daily Pick’em Challenge and win! Play now!

Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow @nathanbeighle_ on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:

Alabama / Arkansas / Auburn / Clemson / Colorado / Florida / Georgia / Iowa / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / USC / Wisconsin / College Football News

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