The No. 24 Oklahoma State Cowboys (7-3, 4-3 Big 12) meet the Oklahoma Sooners (5-5, 2-5) Saturday at Memorial Stadium in Norman, Okla. Kickoff is scheduled for 7:30 p.m. ET (ABC). Below, we analyze Tipico Sportsbook’s lines around the Oklahoma State vs. Oklahoma odds, and make our expert college football picks and predictions.
Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.
The Cowboys check in No. 22 in the College Football Playoff rankings.
Oklahoma State won 20-14 against Iowa State, as QB Spencer Sanders (personal) returned to action in the 4th quarter last week. He asked into the game and led the comeback after sitting out the first 3 quarters after missing practice during the week.
Oklahoma suffered another loss last week, falling 23-20 at West Virginia, a second straight 3-point setback. The Sooners are now 2-5 SU and 1-6 ATS across the past 7 contests. The Under and Over has alternated in each of the past 6 outings.
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Oklahoma State at Oklahoma odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:44 a.m. ET.
- Moneyline (ML): Oklahoma State +200 (bet $100 to win $200) | Oklahoma -250 (bet $250 to win $100)
- Against the spread: Oklahoma State +7 (-114) | Oklahoma -7 (-106)
- Over/Under (O/U): 67 (O: -110 | U: -110)
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Oklahoma State at Oklahoma picks and predictions
Prediction
Oklahoma State 36, Oklahoma 33
Moneyline
OKLAHOMA STATE (+200) is the ranked team here, and the Cowboys are playing slightly better than rival Oklahoma.
The Cowboys’ offense should see a bounce back against a Sooners defense that is allowing 432.3 total yards per game to rank 109th, especially with Sanders expected to play. The Oklahoma defense has been gouged for 200.2 rushing yards to check in 119th, too.
Against the spread
OKLAHOMA STATE +7 (-114) is a super attractive play.
The Cowboys have cashed in 10 of the past 12 games on the road while going 13-4-1 ATS in the past 18 games inside the conference. On the flip side, the Sooners are 1-6 ATS in the past 8 games overall, and 1-6-1 ATS in the past 8 Big 12 games, while going 0-5 ATS in the past 5 at home.
This is a gift, so take advantage.
Over/Under
Play OVER 67 (-110) is the lean, but go lightly.
The Oklahoma State offense is averaging 34.9 PPG to rank 25th in the country, while the Cowboys are allowing 30.0 PPG to rank 101st.
While the Oklahoma offense has been erratic, it is still good for 31.9 PPG, ranking 42nd in the nation, while allowing 29.1 PPG to check in 93rd.
This should be a track meet in one of the final bedlam meetings before Oklahoma departs for the SEC in 2025 and ends the series, at least on a regular basis.
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