SportsbookWire’s NFL Week 4 picks: ML, ATS and O/U predictions for all games

SportsbookWire writers make their NFL Week 4 picks and predictions for money lines, spreads and totals.

Who saw that coming?

The Jacksonville Jaguars, last week’s biggest underdog at 7.5 points, won outright at the Los Angeles Chargers 38-10.

Overall, underdogs went 6-10 against the spread (ATS) and 9-7 straight up (SU) in Week 3. For the season, dogs are 28-19-1 ATS and 12-26-1 SU, according to Covers.com.

As for totals, Unders hold a 30-17-advantage heading into Week 4, which began with the Cincinnati Bengals (1-2) hosting the Miami Dolphins (3-0) Thursday night.

Below are the SportsbookWire staff’s Week 4 NFL picks.

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Sunday’s first game kicks off in London between the Minnesota Vikings (2-1) and New Orleans Saints (1-2), who are the designated home team.

An interesting matchup involves the Buffalo Bills (2-1) at the Baltimore Ravens (2-1) at 1 p.m. ET.

The Sunday night game features QBs Patrick Mahomes and Tom Brady as the Kansas City Chiefs (1-1) visit the Tampa Bay Buccaneers (2-1) at 8:20 p.m. ET.

The week concludes with an NFC West rivalry in the Monday night matchup as the San Francisco 49ers (1-2) host the Los Angeles Rams (2-1) at 8:15 p.m. ET.

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Check out our staff predictions before locking in your Week 4 NFL picks.

NFL Week 4 staff picks

NFL Week 4 odds, picks and predictions

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USA TODAY’s free-to-play Daily Ticket pick ’em contest gives you a chance to show off your skill and win with NFL Week 4 picks and predictions.

USA TODAY’s Daily Ticket lets you show off your NFL knowledge with a free-to-play contest for Sunday’s full slate of games. Visit SportsbookWire.com for help with your NFL picks and predictions and then fill in your selections below for your chance to win.

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Sportsbook Wire’s NFL Week 4 Picks: ML, ATS and OU predictions for all games

Sportsbook Wire writers make their picks and predictions for the money line, spread and total in every game on the NFL’s Week 4 slate.

The Sportsbook Wire team is here to help you with your Week 4 NFL picks. Our writers offer up their selections on the money line, spread and Over/Under for every game on the Week 4 slate. Visit SportsbookWire.com for more NFL picks and predictions throughout the season.

We’re down to five undefeated at 3-0 and another five still looking for their first wins at 0-3. The Tampa Bay Buccaneers and Kansas City Chiefs are not in that prestigious first group but they still share the best odds to win Super Bowl LVI in February.

Check out our staff predictions before locking in your Week 4 NFL picks.

Also see: Week 4 odds and lines

NFL Week 4 staff picks

2021-22 ATS standings

Odds provided by Tipico Sportsbook.

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Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire

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