Fantasy football inactives, injuries and weather: Week 18

Week 18 weather, injury updates and gameday inactives for the fantasy football lineup decisions.

Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 60-90 minutes prior to the kickoff of their game.

Weather forecasts are courtesy of The Football Database.

Week 18 gameday inactives, weather and notes

KEY GAME-TIME DECISIONS

Early games: RB Alvin Kamara (inactive), RB Kendre Miller (active), WR Tee Higgins (inactive), QB Trevor Lawrence (active), WR Christian Kirk (inactive)
Afternoon games: WR Christian Watson (inactive), WR Jayden Reed (active), RB Isiah Pacheco (active), RB D’Andre Swift (inactive)
Sunday night: WR Jaylen Waddle (inactive), RB Raheem Mostert (inactive)


Cleveland Browns at Cincinnati Bengals (1:00 p.m. ET)

Kickoff Weather: 37°F, cloudy, W 12 mph

Browns

Inactives: WR Amari Cooper, WR Marquise Goodwin, PK Dustin Hopkins, CB Mike Ford, CB Greg Newsome, DE Myles Garrett and S Juan Thornhill

Lineup notes: LB Anthony Walker Jr. (knee) was placed on IR. WR Amari Cooper (heel) and PK Dustin Hopkins (hamstring) are out. QB Joe Flacco (calf) and RB Kareem Hunt (groin) all practiced Friday. Flacco will sit out, and it will be surprising if we see much of Hunt. WR Elijah Moore (concussion) is active following a questionable tag. PK Riley Patterson was elevated to the active roster, and PK Dustin Hopkins (hamstring) was ruled out. DE Myles Garrett (shoulder), CB Greg Newsome (knee), and S Juan Thornhill (calf) will not play.

Bengals

Inactives: OT D’Ante Smith, TE Irv Smith, WR Tee Higgins, DT Travis Bell, C Trey Hill, CB Chidobe Awuzie and RB Chris Evans

Lineup notes: WR Tee Higgins (hamstring) will miss another contest after a brief return to the field. WR Ja’Marr Chase (shoulder), RB Joe Mixon (ankle) and QB Jake Browning (foot) practiced Friday and will play.


Minnesota Vikings at Detroit Lions (1:00 p.m. ET)

Kickoff Weather: Dome stadium

Vikings

Inactives: DT Jaquelin Roy, QB Jaren Hall, OG Ed Ingram, CB Theo Jackson, CB Mekhi Blackmon, OT Brian O’Neill and CB Byron Murphy

Lineup notes: TE T.J. Hockenson (knee) went on IR and is out for the season. RT Brian O’Neill (ankle) is out, and LT Christian Darrisaw (illness) is active after being questionable.

Lions

Inactives: WR Jameson Williams, CB Steven Gilmore, TE Brock Wright, DL John Cominsky, DL Brodric Martin, QB Hendon Hooker and DE Charles Harris

Lineup notes: WR Jameson Williams (ankle) is out. LT Taylor Decker (groin), C Frank Ragnow (knee, back, toe) and TE Sam LaPorta (ankle) are good to go after a full practice Friday. DB Chauncey Gardner-Johnson (pectoral) was activated from IR and is not on the injury report.


Jacksonville Jaguars at Tennessee Titans (1:00 p.m. ET)

Kickoff Weather: 40°F, cloudy

Jaguars

Inactives: WR Christian Kirk, DT Angelo Blackson, OG Cole Van Lanen, QB Matt Barkley and LB Yasir Abdullah

Lineup notes: QB Trevor Lawrence (shoulder) will gut it out. WR Zay Jones (knee, hamstring) also will give it a whirl, though WR Christian Kirk (groin) isn’t quite ready yet, despite being activated from IR on Saturday.

Titans

Inactives: CB Anthony Kendall, DL TK McClendon Jr., DL Caleb Murphy, LB Trevis Gipson, OT Jaelyn Duncan, QB Will Levis and OT Daniel Brunskill

Lineup notes: QB Will Levis (foot) is inactive after being questionable, but QB Ryan Tannehill was named the starter anyway. CB Caleb Farley (back) has been ruled out.


New York Jets at New England Patriots (1:00 p.m. ET)

Kickoff Weather: 32°F, 95% chance of snow, NNE 15 mph

Jets

Inactives: QB Aaron Rodgers, LB Marcelino McCrary-Ball, DE Carl Lawson, WR Allen Lazard, PK Austin Seibert, OT Austin Deculus and CB Bryce Hall

Lineup notes: QB Aaron Rodgers (Achilles) is out, and QB Zach Wilson (concussion) went on IR.

Patriots

Inactives: QB Mac Jones, DT Sam Roberts, RB JaMycal Hasty, S Joshuah Bledsoe, OT Trent Brown, WR Tyquan Thornton and TE La’Michael Pettway

Lineup notes: WR JuJu Smith-Schuster (ankle) went on IR, ending his season. TE Hunter Henry (knee) also went on IR. LT Trent Brown (illness) is out. WR DeVante Parker (ribs) is active, but WR Tyquan Thornton (ankle) won’t go.


Atlanta Falcons at New Orleans Saints (1:00 p.m. ET)

Kickoff Weather: Dome stadium

Falcons

Inactives: QB Taylor Heinicke, S DeMarcco Hellams, DT Tommy Togiai, C Drew Dalman, DB Natrone Brooks and DE Zach Harrison

Lineup notes: QB Taylor Heinicke (ankle) will not be available, so look for QB Desmond Ridder to start the finale.

Saints

Inactives: RB Alvin Kamara, WR Keith Kirkwood, LB Monty Rice, QB Jake Haener, DL Kyle Phillips, OT Landon Young and CB Lonnie Johnson

Lineup notes: RT Ryan Ramczyk (knee) went on IR. RB Alvin Kamara (ankle) won’t play, but RB Kendre Miller (ankle, illness) and TE Juwan Johnson (chest) are active despite being questionable.WR Chris Olave (ankle) was limited early in the week, but he had a full session Friday and will go. RB Jordan Mims was elevated from the practice squad.


Tampa Bay Buccaneers at Carolina Panthers (1:00 p.m. ET)

Kickoff Weather: 48°F, cloudy, W 12 mph

Buccaneers

Inactives: QB John Wolford, LB K.J. Britt, OT Brandon Walton, WR Rakim Jarrett and LB Markees Watts

Lineup notes: QB Baker Mayfield (ribs), WR Trey Palmer (hip), and CB Carlton Davis (concussion) are active, despite being listed as questionable.

Panthers

Inactives: CB Shaquill Griffin, OT Ilm Manning, DE Marquis Haynes, OG Cade Mays, WR Mike Strachan, PK Eddy Pineiro and OT Ricky Lee

Lineup notes: WR Jonathan Mingo (foot) was placed on IR. PK Eddy Pineiro (hamstring) is inactive. QB Bryce Young (back) and RT Taylor Moton (knee) practiced all week and will play. WR DJ Chark Jr. (foot) had full sessions Thursday and Friday and will go. CB Jaycee Horn (toe) is active after being questionable.


Late afternoon games

Chicago Bears at Green Bay Packers (4:25 p.m. ET)

Kickoff Weather: 34°F, cloudy, WNW 10 mph

Bears

Inactives: CB Jaylon Johnson, S Quindell Johnson, QB Tyson Bagent, RB D’Onta Foreman, CB Greg Stroman, OT Ja’Tyre Carter and WR Darnell Mooney

Lineup notes: WR Darnell Mooney (concussion) is out again. TE Cole Kmet (knee) and RB Khalil Herbert (back) are active. RB D’Onta Foreman is a healthy scratch once again. C Lucas Patrick (knee) was placed on IR. WR DJ Moore (ankle) practiced Friday and will play.

Packers

Inactives: LB Isaiah McDuffie, RB AJ Dillon, DL Brenton Cox, OT Caleb Jones, WR Christian Watson and WR Grant DuBose

Lineup notes: RB AJ Dillon (thumb, neck) is out. TE Luke Musgrave (kidney) was activated from IR. WR Christian Watson (hamstring) won’t go, but WR Dontayvion Wicks (chest), WR Jayden Reed (chest) and LG Elgton Jenkins (knee, ankle) are active. RB Aaron Jones (knee, finger) was limited all week but doesn’t have an injury tag.


Denver Broncos at Las Vegas Raiders (4:25 p.m. ET)

Kickoff Weather: Dome stadium

Broncos

Inactives: C Alex Forsyth, CB Art Green, WR Michael Bandy, DL Thomas Incoom, DT Elijah Garcia and TE Chris Manhertz

Lineup notes: WR Courtland Sutton (concussion) and WR Marvin Mims (hamstring) practiced Friday and are good to go. RT Mike McGlinchey (ribs) has been placed on IR.

Raiders

Inactives: RB Josh Jacobs, OT Thayer Munford, WR Keelan Cole, DB Tyler Hall, DB Jaydon Grant, QB Brian Hoyer and DL Byron X. Young

Lineup notes: RB Josh Jacobs (quadriceps) and TE Michael Mayer (toe) are out.


Philadelphia Eagles at New York Giants (4:25 p.m. ET)

Kickoff Weather: 37°F, cloudy

Eagles

Inactives: WR DeVonta Smith, DL Fletcher Cox, QB Tanner McKee, OT Tyler Steen, RB D’Andre Swift and CB Darius Slay

Lineup notes: WR DeVonta Smith (ankle) and CB Darius Slay (knee) are out. RB D’Andre Swift (illness) also is inactive.

Giants

Inactives: DL Timmy Horne, QB Jacob Eason, LB Benton Whitley, TE Tyree Jackson, CB Deonte Banks, WR Parris Campbell and C John Michael Schmitz

Lineup notes: C John Michael Schmitz (shin) is inactive. QB Tyrod Taylor (back) was limited all week but will play.


Seattle Seahawks at Arizona Cardinals (4:25 p.m. ET)

Kickoff Weather: 50°F, clear, W 14 mph (retractable-roof dome)

SEahawks

Inactives: OT Abraham Lucas, OT Raiqwon O’Neal, RB Kenny McIntosh, DL Jarran Reed, OT Jason Peters, DL Mario Edwards Jr. and LB Patrick O’Connell

Lineup notes: RT Abraham Lucas (knee) is out. RB Kenneth Walker III (shoulder) and WR Tyler Lockett (toe) practiced Friday and will go. LB Jordyn Brooks (ankle) is active.

Cardinals

Inactives: OT Dennis Daley, LB Trevor Nowaske, CB Divaad Wilson, TE Blake Whiteheart, CB Garrett Williams, DE Cameron Thomas and OT Carter O’Donnell

Lineup notes: LT D.J. Humphries (knee) was placed on IR with a torn ACL. WR Marquise Brown (heel) went on IR and is out for the season. WR Zach Pascal (hamstring) is active.


Kansas City Chiefs at Los Angeles Chargers (4:25 p.m. ET)

Kickoff Weather: 55°F, clear N 17 mph (open-air dome)

Chiefs

Inactives: QB Patrick Mahomes, OT Donovan Smith, WR Rashee Rice, DE Mike Danna, TE Travis Kelce, WR Kadarius Toney and CB L’Jarius Sneed

Lineup notes: WR Rashee Rice (hamstring), LT Donovan Smith (neck) and WR Kadarius Toney (hip, ankle) are out. QB Patrick Mahomes (ankle) is out. RB Isiah Pacheco (concussion, shoulder) is active but probably won’t see much, if any, action. TE Travis Kelce (neck) and DE Michael Danna (coaching decision) also will be rested. TE Noah Gray (ribs) is good to go after practicing all week. LB Nick Bolton (wrist, abdomen), DE George Karlaftis (coaching decision), and CB Trent McDuffie (shoulder) are active, but it will be surprising of they play much. CB L’Jarius Sneed is out.

Chargers

Inactives: WR Keenan Allen, RB Isaiah Spiller, LB Kenneth Murray, WR Jalen Guyton, DL Nick Williams, OG Zion Johnson and S JT Woods

Lineup notes: EDGE Joey Bosa (foot) and WR Keenan Allen (heel) are out. LB Kenneth Murray (shoulder) joins them after being deemed doubtful. WR Joshua Palmer (concussion) practiced fully Friday and will go. LG Zion Johnson (neck) also is out.


Los Angeles Rams at San Francisco 49ers (4:25 p.m. ET)

Kickoff Weather: 49°F, mostly clear

Rams

Inactives: DL Aaron Donald, QB Matthew Stafford, WR Cooper Kupp, OT Joe Noteboom, TE Tyler Higbee, RB Kyren Williams and LB Ernest Jones

Lineup notes: WR Cooper Kupp (rest), RB Kyren Williams (rest), DT Aaron Donald (rest), QB Matthew Stafford (rest) and TE Tyler Higbee (shoulder) are inactive. QB Carson Wentz will start. Don’t expect to see much, if anything, from WR Puka Nacua.

49ers

Inactives: CB Ambry Thomas, DL Arik Armstead, S Tashaun Gipson, WR Jauan Jennings, QB Brock Purdy, S Ji’Ayir Brown and RB Christian McCaffrey

Lineup notes: RB Christian McCaffrey (calf) is out. RB Elijah Mitchell (illness) is set to play after a full session Friday. DT Arik Armstead (foot/knee) was ruled out. QB Brock Purdy (coach’s decision) will sit in favor of QB Sam Darnold.


Dallas Cowboys at Washington Commanders (4:25 p.m. ET)

Kickoff Weather: 44°F, cloudy, W 13 mph

Cowboys

Inactives: CB Noah Igbinoghene, QB Trey Lance, OG Tyler Smith, CB Eric Scott Jr., DL Viliami Fehoko Jr., OG Zack Martin and S Sheldrick Redwine

Lineup notes: RB Deuce Vaughn (ankle) landed on IR. RB Rico Dowdle (ankle) will return after practicing Thursday and Friday. LG Tyler Smith (foot) and RG Zack Martin (illness) are inactive, but C Tyler Biadasz (illness) will go.

Commanders

Inactives: DE Jonathan Allen, TE Cole Turner, LB Andre Jones Jr., OG Andrew Wylie, QB Jacoby Brissett, S Kamren Curl and LB Casey Toohill

Lineup notes: RT Andrew Wylie (elbow) and QB Jacoby Brissett (hamstring) are inactive. WR Curtis Samuel (hamstring) practiced fully Friday and is good to go. QB Sam Howell will start. DE Jonathan Allen (knee) and S Kam Curl (quad) will not be available.


Sunday Night Football

Buffalo Bills at Miami Dolphins (8:20 p.m. ET)

Kickoff Weather: 60°F, mostly cloudy, 80% humidity

Bills

Inactives: OG Alec Anderson, CB Kaiir Elam, DL Kingsley Jonathan, RB Latavius Murray, S Damar Hamlin and DL Linval Joseph

Lineup notes: C Mitch Morse (illness) was questionable after he sat out of practice Friday but has been since removed from the report. QB Josh Allen (neck, finger) practiced all week and is good to go. RB Leonard Fournette was elevated from the practice squad.

Dolphins

Inactives: RB Raheem Mostert, DB Ethan Bonner, OT Kion Smith, QB Skylar Thompson, WR Jaylen Waddle, TE Tyler Kroft and CB Xavien Howard

Lineup notes: WR Jaylen Waddle (ankle) and RB Raheem Mostert (knee, ankle) will miss this game. WR Tyreek Hill (ankle), QB Tua Tagovailoa (shoulder, quadriceps), RB De’Von Achane (toe, ribs), LT Terron Armstead (knee, ankle, back), RG Robert Hunt (hamstring) and RT Austin Jackson (oblique) practiced Friday and will play. CB Xavien Howard (foot) has been ruled out. S Jevon Holland (knees) was added Saturday as questionable but is active.

Gameday inactives, injuries and weather: Week 18

Week 18 weather, injury updates and gameday inactives for the fantasy football lineup decisions.

Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 60-90 minutes prior to the kickoff of their game.

Weather forecasts are courtesy of The Football Database.

Week 18 gameday inactives, weather and notes

KEY GAME-TIME DECISIONS

Early games: RB D’Onta Foreman (active), TE Taysom Hill (active), TE Juwan Johnson (active), WR Jakobi Meyers (active)
Afternoon games: WR Tyler Lockett (active), QB Jalen Hurts (active)
Sunday night:

Tampa Bay Buccaneers at Atlanta Falcons (1:00 p.m. EST)

Kickoff Weather: Dome stadium

Buccaneers

Inactives: CB Logan Ryan, OT Donovan Smith, WR Julio Jones, S Mike Edwards, DT Vita Vea, DL Carl Nassib and CB Carlton Davis

Lineup notes: WR Julio Jones (knee, illness) will sit out the regular-season finale. CB Carlton Davis (shoulder), S Logan Ryan (knee), OT Donovan Smith (foot) and DT Vita Vea (calf) also will not play. With nothing at stake, Tampa could opt to rest most of its key players at some point during the contest.

Falcons

Inactives: DL David Anenih, DL Jalen Dalton, CB Rashad Fenton, S Micah Abernathy, OT Elijah Wilkinson and TE Feleipe Franks

Lineup notes: No injuries of fantasy relevance.

Houston Texans at Indianapolis Colts (1:00 p.m. EST)

Kickoff Weather: 34 degrees, overcast (retractable-roof dome)

Texans

Inactives: QB Kyle Allen, C Jimmy Morrissey, CB Steven Nelson, DT Thomas Booker, TE O.J. Howard and WR Phillip Dorsett

Lineup notes: No injuries of fantasy relevance.

Colts

Inactives: CB Stephon Gilmore, QB Nick Foles, S Nick Cross, C Wesley French, LB Rashod Berry, DT Chris Z. Williams and TE Kylen Granson

Lineup notes: QB Nick Foles (ribs) is out, so Sam Ehlinger will start. CB Stephon Gilmore (wrist) will miss the finale.

Baltimore Ravens at Cincinnati Bengals (1:00 p.m. EST)

Kickoff Weather: 37 degrees, overcast

Ravens

Inactives: CB Marcus Peters, TE Mark Andrews, CB Brandon Stephens, OG Kevin Zeitler, QB Tyler Huntley, RB J.K. Dobbins, DL Rayshad Nichols and QB Lamar Jackson

Lineup notes: QB Lamar Jackson (knee) is out once again. QB Tyler Huntley (shoulder, wrist) and CB Marcus Peters (calf) were questionable but won’t go. Baltimore is resting TE Mark Andrews, OG Kevin Zeitler and RB J.K. Dobbins.

Bengals

Inactives: OT D’Ante Smith, QB Jake Browning, CB Jalen Davis, TE Devin Asiasi, DE Jeffrey Gunter and RB Chris Evans

Lineup notes: No injuries of fantasy relevance.

New England Patriots at Buffalo Bills (1:00 p.m. EST)

Kickoff Weather: 32 degrees, partly cloudy

Patriots

Inactives: CB Jalen Mills, DT Sam Roberts, S Brenden Schooler, CB Shaun Wade, TE Jonnu Smith, S Joshuah Bledsoe and RB Kevin Harris

Lineup notes: TE Jonnu Smith (concussion) was downgraded on Saturday and will not play. WR Jakobi Meyers (shoulder) will give it a whirl, and WR DeVante Parker (concussion) also is good to go.

Bills

Inactives: LB Baylon Spector, S Jared Mayden, TE Tommy Sweeney, CB Christian Benford, OT Justin Murray and OL Ike Boettger

Lineup notes: QB Josh Allen (elbow, ankle) continues to play through multiple ailments.

New York Jets at Miami Dolphins (1:00 p.m. EST)

Kickoff Weather: 78 degrees, clear

Jets

Inactives: WR Irvin Charles, RB James Robinson, DE Bradlee Anae, QB Mike White and TE C.J. Uzomah

Lineup notes: QB Mike White (rib) will not play, so QB Joe Flacco is making the start. OT Duane Brown has been placed on IR.

Dolphins

Inactives: TE Tanner Conner, OT Terron Armstead, CB Noah Igbinoghene, QB Tua Tagovailoa, LB Brennan Scarlett, WR Cedrick Wilson and OL Kendall Lamm

Lineup notes: QB Tua Tagovailoa (concussion) is out. QB Teddy Bridgewater (knee, finger) is available, but Skylar Thompson draws the start. WR Jaylen Waddle (shoulder) continues to play through the shoulder injury. OT Terron Armstead (toe, pec, knee, hip) won’t go, while LB Bradley Chubb (ankle, hand) and CB Xavien Howard (knee) are playing through questionable designations.

Minnesota Vikings at Chicago Bears (1:00 p.m. EST)

Kickoff Weather: 31 degrees, overcast

Vikings

Inactives: S Harrison Smith, DE James Lynch, LB Za’Darius Smith, LB Brian Asamoah, C Garrett Bradbury, CB Cameron Dantzler and DL Ross Blacklock

Lineup notes: TE Irv Smith was activated from IR but remains a backup. S Harrison Smith (knee) and C Garrett Bradbury (back) have been ruled out.

Bears

Inactives: RB Darrynton Evans, CB Kyler Gordon, S Sterling Weatherford, DT Angelo Blackson, LB Terrell Lewis, DB Jaylon Jones and QB Justin Fields

Lineup notes: QB Justin Fields (hip) has been ruled out.

Carolina Panthers at New Orleans Saints (1:00 p.m. EST)

Kickoff Weather: Dome stadium

Panthers

Inactives: DT Matt Ioannidis, DE Brian Burns, CB Juston Burris, WR Rashard Higgins, OT Larnel Coleman, LB Chandler Wooten and C Sam Tecklenburg

Lineup notes: CB Jaycee Horn (wrist) was placed on IR. RB D’Onta Foreman (knee) was limited Friday but will be out there. DE Brian Burns (ankle) was a DNP in Friday’s practice and is idle today.

Saints

Inactives: TE J.P. Holtz, WR Kirk Merritt, OT Ryan Ramczyk, S Marcus Maye, OG Andrus Peat, S Justin Evans, CB Paulson Adebo and DL Payton Turner

Lineup notes: TEs Taysom Hill (back) and Juwan Johnson (quadriceps) will play through questionable listings. OG Andrus Peat (ankle) and OT Ryan Ramczyk (hip) are out.

Cleveland Browns at Pittsburgh Steelers (1:00 p.m. EST)

Kickoff Weather: 34 degrees, mostly cloudy

Browns

Inactives: DE Isaiah Thomas, OT Jack Conklin, RB Demetric Felton, DT Ben Stille, DE Jadeveon Clowney, QB Kellen Mond and DB Thomas Graham

Lineup notes: DE Jadeveon Clowney (not injury related) and RT Jack Conklin (ankle) will not be available for the finale. CB Denzel Ward (shoulder) will play.

Steelers

Inactives: LB Malik Reed, QB Mason Rudolph, DT Jonathan Marshall, LB Tae Crowder, CB Tre Norwood and OG Kendrick Green

Lineup notes: WR Diontae Johnson (hip) is good to go. S Minkah Fitzpatrick (ankle) and LB Myles Jack (groin) also will be out there, despite drawing questionable tags.

Dallas Cowboys at Washington Commanders (4:25 p.m. EST)

Kickoff Weather: 40 degrees, clear

Cowboys

Inactives: WR Jalen Tolbert, S Markquese Bell, C Tyler Biadasz, LB Leighton Vander Esch, QB Will Grier, CB Israel Mukuamu and DT Quinton Bohanna

Lineup notes: RB Tony Pollard (thigh) will return this week.

Commanders

Inactives: DE Jonathan Allen, OG Andrew Norwell, S Kamren Curl, OT Cornelius Lucas, DL James Smith-Williams, RB Brian Robinson Jr. and QB Carson Wentz

Lineup notes: RB Antonio Gibson (knee, ankle) went on IR. RB Brian Robinson Jr. (knee) and DT Jonathan Allen (knee) are out. LB Jamin Davis (knee) was placed on IR, and S Kam Curl (ankle) was downgraded to out. RB Reggie Bonnafon was elevated to the active roster.

Los Angeles Chargers at Denver Broncos (4:25 p.m. EST)

Kickoff Weather: 45 degrees, partly cloudy

Chargers

Inactives: OT Storm Norton, WR Michael Bandy, DT Tyeler Davison, CB Bryce Callahan, QB Easton Stick, RB Zander Horvath and RB Isaiah Spiller

Lineup notes: S Derwin James (concussion) will play. If the Ravens lose in the early window, LA may sit its key players.

Broncos

Inactives: DT D.J. Jones, WR Kendall Hinton, CB Damarri Mathis, QB Jarrett Guarantano, OT Calvin Anderson, DL Jonathan Kongbo and WR Montrell Washington

Lineup notes: WR Jerry Jeudy (ankle) was a full-go Friday and will play. RB Marlon Mack (hamstring) was placed on IR.

New York Giants at Philadelphia Eagles (4:25 p.m. EST)

Kickoff Weather: 40 degrees, mostly cloudy

Giants

Inactives: CB Adoree’ Jackson, OT Andrew Thomas, LB Azeez Ojulari, DT Dexter Lawrence, CB Julian Love, DL Leonard Williams and RB Saquon Barkley

Lineup notes: LB Azeez Ojulari (ankle) and DT Leonard Williams (neck) will not be out there. RB Saquon Barkley will not play to preserve him for the playoffs, and New York could opt to rest other key players.

Eagles

Inactives: OT Lane Johnson, CB Avonte Maddox, DE Josh Sweat, RB Trey Sermon and QB Ian Book

Lineup notes: RT Lane Johnson (groin) will not play. QB Jalen Hurts (shoulder) will make his return to action. RB Miles Sanders (knee) managed a full session in Friday and will play. S C.J. Gardner-Johnson and DE Robert Quinn were activated from the Reserve/Injured list.

Los Angeles Rams at Seattle Seahawks (4:25 p.m. EST)

Kickoff Weather: 47 degrees, 62% chance of light rain, S 10 mph

Rams

Inactives: CB Shaun Jolly, DL Aaron Donald, LB Travin Howard, QB John Wolford, WR Ben Skowronek and C Brian Allen

Lineup notes: DT Aaron Donald (ankle) and WR Ben Skowronek (calf) remain out.

Seahawks

Inactives: CB Artie Burns, WR Penny Hart, OG Phil Haynes, LB Vi Jones, DE Joshua Onujiogu, DB Ryan Neal and DT Isaiah Mack

Lineup notes: RB Travis Homer (ankle) and LB Jordyn Brooks (knee) were placed on IR. WR Tyler Lockett (shin) overcame his questionable tag. RB DeeJay Dallas (ankle), RB Kenneth Walker III (ankle, illness) and TE Noah Fant (knee) will play.

Arizona Cardinals at San Francisco 49ers (4:25 p.m. EST)

Kickoff Weather: 58 degrees, mostly cloudy

Cardinals

Inactives: RB James Conner, OG Lecitus Smith, WR Robbie Anderson, QB Colt McCoy, CB Marco Wilson, CB Antonio Hamilton, WR DeAndre Hopkins, DL Zach Allen and LB Zaven Collins

Lineup notes: WR DeAndre Hopkins (knee), QB Colt McCoy (concussion), RB James Conner (knee, shin), WR Robby Anderson (back) and LB Zaven Collins (calf) are all out. WR Marquise Brown (wrist) will play.

49ers

Inactives: OG Aaron Banks, DT Kevin Givens, CB Ambry Thomas, DE Drake Z. Jackson, QB Jimmy Garoppolo, LB Dre Greenlaw and TE Ross Dwelley

Lineup notes: LB Dre Greenlaw (back) will not play. QB Jimmy Garoppolo (foot) didn’t practice all week and is out. On the bright side, WR Deebo Samuel (quadriceps) mustered a full session in Friday and will return. RB Elijah Mitchell also is set to come back to action after being activated from IR. DE Nick Bosa (hamstring) should be out there, but could be on a snap count. RB Christian McCaffrey (knee) completed a full session in Friday and will play. QB Brock Purdy (oblique, rib) practiced all week and is fine. DT Arik Armstead (foot, ankle) and DT Javon Kinlaw (illness, knee) are questionable.

Sunday Night Football

Detroit Lions at Green Bay Packers (8:20 p.m. EST)

Kickoff Weather: 24 degrees, mostly cloudy

Lions

Inactives: OG Kayode Awosika, RB Craig Reynolds, CB Jeff Okudah, RB Jermar Jefferson, DE Austin Bryant, DL Michael Brockers and OG Ross Pierschbacher

Lineup notes: CB Jeff Okudah (elbow)iis inactive.

Packers

Inactives: DT Jonathan Ford, CB Shemar Jean-Charles, WR Bo Melton, OT Caleb Jones and OT Rasheed Walker

Lineup notes: QB Aaron Rodgers (thumb, knee) will continue playing through multiple injuries.