NFL Week 16 odds and lines: Money line, spread and Over/Under for all games

Looking at the NFL odds and lines for the Week 16 slate, with money lines, spreads and Over/Unders for all games.

The Detroit Lions (2-10-1) picked up their second win in three weeks with a 30-12 defeat of the Arizona Cardinals (30-12) and the Tampa Bay Buccaneers (10-4) were held scoreless in a 9-0 loss to the New Orleans Saints (7-7) in major Week 15 upsets. Below, we look at the Week 15 NFL odds and lines; check back for our NFL picks and predictions.

Week 16 gets underway with a Thursday meeting between the San Francisco 49ers (8-6) and suddenly skidding Tennessee Titans (9-4). Christmas Day features more cross-conference play with the Cleveland Browns (7-6) visiting the Green Bay Packers (11-3) and the Indianapolis Colts (8-6) in the desert for a tilt with the Arizona Cardinals (10-4). Sunday’s play is highlighted with a rematch of the Buffalo Bills (8-6) and New England Patriots (9-5).

Odds provided by Tipico Sportsbook and last updated Monday, Dec. 20.

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