Week 10’s marquee game features the NFC North-leading Minnesota Vikings (7-1) visiting the Buffalo Bills (6-2), who sit atop the AFC East, Sunday at 1 p.m. ET (FOX). However, Bills QB Josh Allen’s status is in question after he injured his elbow late in last week’s 20-17 loss at the New York Jets.
The week opened with the Carolina Panthers (3-7) claiming a 25-15 home win as 2.5-point underdogs over the Atlanta Falcons (4-6) on Thursday Night Football.
The Panthers-Falcons NFC South matchup is 1 of 4 division rivalries on the Week 10 slate. The other 3 are:
– All Sunday and ET unless noted
- NFC North: Detroit Lions (2-6) at Chicago Bears (3-6), 1 p.m. (FOX)
- NFC West: Arizona Cardinals (3-6) at Los Angeles Rams (3-5), 4:25 p.m. (FOX)
- NFC East: Washington Commanders (4-5) at Philadelphia Eagles (8-0), Monday, 8:15 p.m. (ESPN)
Check out: SportsbookWire’s latest NFL picks and predictions
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Sunday action kicks off from Munich, Germany, with the Seattle Seahawks (6-3) facing the Tampa Bay Buccaneers (4-5) at 9:30 a.m. ET (NFL Network) — the Bucs are the designated home team.
The final 2 prime-time games have the San Francisco 49ers (4-4) hosting the Los Angeles Chargers (5-3) Sunday for an 8:20 p.m. ET kickoff (NBC), while the Eagles will look to improve to 9-0 when they welcome the Commanders Monday night.
Four teams are on byes: The Baltimore Ravens (6-3), Cincinnati Bengals (5-4), New England Patriots (5-4), New York Jets (6-3).
Before looking at SportsbookWire staff’s Week 10 NFL picks, here are straight up (SU), against the spread (ATS) and Over/Under records through the first 9 weeks.
Favorites went 9-4 straight up (SU) in Week 9 but were 4-7-2 against the spread (ATS). For the season, favorites are 81-54-1 SU, while underdogs hold a 76-57-3 ATS advantage.
Unders increased their overall lead to 81-54-1 after a 9-4 showing last week.
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NFL Week 10 staff picks
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