SportsbookWire’s NFL Week 1 Picks: ML, ATS and OU predictions for all games

SportsbookWire writers make their NFL Week 1 picks and predictions for money lines, spreads and totals.

Finally!

The new NFL season is here and the SportsbookWire team is here to help you with your Week 1 NFL picks. Our writers offer up their selections on the money line, spread and Over/Under for every game of the Week 1 slate.

Opening week kicked off with the Buffalo Bills, the Super Bowl favorites, visiting the defending champions Los Angeles Rams Thursday night at SoFi Stadium.

Josh Allen and Co. began the season listed by Tipico Sportsbook at +500 (5 to 10) to win Super Bowl LVII – scheduled for Feb. 12, 2023 at State Farm Arena in Glendale, Ariz. The Rams are tied for the 5th shortest odds at +1200.

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There are 6 Week 1 games involving division rivalries, highlighted by 2 Sunday tilts at 4:25 ET: Packers at Vikings and Raiders at Chargers.

The Sunday night game features the Cowboys hosting Tom Brady and the Buccaneers at 8:20 p.m. ET, while Monday night offers the Broncos and their new QB Russell Wilson visiting his former team in the Seahawks at 8:15 p.m. ET.

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Check out our staff predictions before locking in your Week 1 NFL picks.

Also see: Week 1 odds and lines

NFL Week 1 staff picks

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