San Francisco 49ers at New York Jets odds, picks and best bets

Previewing the San Francisco 49ers at New York Jets Week 2 betting odds and lines, with NFL betting picks, tips and best bets.

The San Francisco 49ers (0-1) and New York Jets (0-1) will both go for their first win of the 2020 NFL season Sunday in Week 2 at MetLife Stadium in East Rutherford, N.J. Kickoff is at 1 p.m. ET. Below, we preview the 49ers-Jets betting odds and lines and make our NFL picks and best bets.

49ers at Jets betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 5 p.m. ET.

  • Money line: 49ers -304 (bet $304, win $100) | Jets +250 (Bet $100, win $250)
  • Against the spread/ATS: 49ers -7 (-110) | Jets +7 (-110)
  • Over/Under: 42.5 (O: -110, U: -110)

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49ers at Jets game notes

  • The Niners suffered a 24-20 home loss against the NFC West rival Arizona Cardinals in Week 1. They closed as 7-point favorites. The Jets lost 27-17 on the road against the AFC East rival Buffalo Bills as 6.5-point road dogs.
  • The Jets went Over their projected point total against the Bills by 4.5 points. The Niners and Cards fell 4.5 points shy of their projected total.
  • The two cross-conference opponents haven’t played since the 2016 season. The Jets won 23-17. Bryce Petty and Colin Kaepernick started at quarterback for the Jets and 49ers, respectively.
  • 49ers QB Jimmy Garoppolo went 19-for-33 through the air for 259 yards and two touchdowns last week. Jets QB Sam Darnold was 21-for-35 for 215 yards with one TD and one interception.
  • San Francisco was plus-1 in turnover differential last week. New York was neutral with two giveaways and two takeaways.

49ers at Jets key injuries

49ers

  • TE George Kittle (knee) questionable
  • CB Ahkello Witherspoon (concussion) questionable

Jets

  • RB Le’Veon Bell (hamstring) out
  • OT Mekhi Becton (knee) questionable
  • WR Jamison Crowder (hamstring) questionable

49ers at Jets: Odds, betting lines, picks and prediction

Prediction

49ers 24, Jets 10

Money line (?)

The 49ers (-304) are heavy road favorites coming off the loss in their home opener. We’ll PASS on a money line bet, as the Niners are far too chalky and there aren’t odds high enough to make the Jets (+250) an enticing play after their Week 1 showing.

New York managed just 254 total yards of offense last week and lost RB Le’Veon Bell (hamstring) to injured reserve until at least Week 5. The Niners may not have a fully healthy Kittle, but he should be expected to take the field with rookie WR Brandon Aiyuk set to make his NFL debut after missing Week 1 due to injury.

The reigning NFC champion 49ers are the more talented team at every position group. They’ll respond from a Week 1 upset, but we’ll find our betting value on the spread.

Against the spread (?)

Take the 49ERS -7 (-110) to win by 8 or more points. Following Week 1, they’re still +1100 to make it back to the Super Bowl by the NFL futures odds at BetMGM; the Jets are +10000.

The Niners are expecting to have a healthier receiving corps in Week 2, and they’ll again lean on RB Raheem Mostert and the rushing game. The Jets have no semblance of a functioning offense one week into the season and should be bet against until offering some sign of life.

Over/Under (?)

Take the UNDER 42.5 (-110) and don’t sweat it too much. The 49ers won’t be able to blow anybody out of the water until getting healthier in the passing game; WR Deebo Samuel (foot) is on injured reserve. The Jets may be a few drafts away contributing their share toward the projected point total.

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