San Francisco 49ers road favorites vs. New York Giants in Week 3

The New York Giants are home underdogs in Week 3 as they host the San Francisco 49ers.

A banged-up San Francisco 49ers (1-1) team still opened as four-point favorites in Week 3 on the road against the New York Giants (0-2). Kick-off is scheduled for 1 p.m. ET at MetLife Stadium. Lets look at the early Week 3 betting odds and lines at BetMGM Sportsbook.

New York mounted a comeback against the Chicago Bears in Week 2 but came up short, 17-13. The Giants lost Pro Bowl RB Saquon Barkley in the first quarter in what’s feared to be a torn ACL and QB Daniel Jones’ turnover woes surfaced again, as he threw a pick and lost a fumble in Week 2.

San Francisco suffered even bigger losses, and on both sides of the ball, in its 31-13 Week 2 stomping of the New York Jets. QB Jimmy Garoppolo and RB Raheem Mostert went out for the offense, while DE Nick Bosa and DT Solomon Thomas also went down with injuries.

49ers at Giants betting odds, spread and line

Odds via BetMGM; last updated Monday at 9:30 a.m. ET.

  • Money line: Giants +170 (bet $100 to win $170) / 49ers -200 (bet $200 to win $100) | Bet now
  • Against the spread: Giants +4, -110 (bet $110 to win $100) / 49ers -4, -110 (bet $110 to win $100) | Bet now
  • Total: 41.5, Over -110 (bet $110 to win $100) / Under -110 (bet $110 to win $100) | Bet now

New to NFL betting?

The 49ers are -200 favorites with a 66.67% implied win probability, 1/2 fractional odds and 1.50 decimal odds. If San Francisco wins by five or more points than the 49ers’ -4 (-110) ticket cashes.

New York comes in as +170 underdogs with a 37.04% implied win probability, 17/10 fractional odds and 2.70 decimal odds. If New York upsets San Francisco or loses by three or fewer points than the Giants -4 (-110) is a winning bet.

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