The Arizona Cardinals (1-0) play their home opener Sunday of Week 2 when they host the Minnesota Vikings (0-1). Kickoff at State Farm Stadium is set for 4:05 p.m ET. Below, we look at the Vikings vs. Cardinals odds and lines; check back for our NFL picks and predictions.
The Vikings dropped their season opener 27-24 to the Cincinnati Bengals in overtime. They outgained the Bengals 403-366 in total yards and held them to only 3-of-14 on third-down conversions.
QB Kirk Cousins had 351 passing yards and 2 touchdown passes but was unable to overcome the team taking 12 penalties for 116 yards. Minnesota K Greg Joseph kicked a game-tying field goal as time expired in regulation to force overtime. Star RB Dalvin Cook committed a costly fumble on the Cincinnati 38 yard line to give the Bengals possession in the final minutes of extra time which allowed them to set up the game-winning field goal.
The Cardinals were dominant in their 38-13 defeat of the Tennessee Titans in Week 1. QB Kyler Murray threw 4 touchdown passes and rushed for a score, while LB Chandler Jones had 5 sacks and 2 forced fumbles.
Arizona limited Tennessee to 248 total yards and held 2019 and 2020 rushing champion, RB Derrick Henry, to only 58 yards on 17 carries.
Vikings at Cardinals odds, spread and line
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 7:47 a.m. ET.
- Money line: Vikings +170 (bet $100 to win $170) | Cardinals -210 (bet $210 to win $100)
- Against the spread (ATS): Viknigs +4.5, -112 (bet $112 to win $100) | Cardinals -4.5, -108 (bet $108 to win $100)
- Total (O/U): 51.5, Over -103 (bet $103 to win $100) | Under -117 (bet $117 to win $100)
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2021 betting stats:
- ML: Vikings 0-1 | Cardinals 1-0
- ATS: Vikings 0-1 | Cardinals 1-0
- O/U: Vikings 1-0 | Cardinals 0-1
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Cardinals at Vikings head-to-head
The Vikings lead the all-time series 17-11 and have won 12 of the last 15 matchups. However, they have not won in Arizona since 2008, as the Cardinals are 2-0 at home against Minnesota since then.
Cousins is 2-2 in four career starts against the Cardinals and has completed 64.4% of his passes for 1,054 yards, 6 touchdowns and 5 interceptions. He has been sacked nine times in those four games.
They last faced one another in 2018, the season before Murray entered the NFL.
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