Michigan State at Oregon odds, picks and predictions

Analyzing Friday’s Michigan State at Oregon odds and lines, with college football expert picks, predictions and best bets.

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The Michigan State Spartans (3-2, 1-1 Big Ten) visit the 6th-ranked Oregon Ducks (4-0, 1-0) Friday in the 1st Big Ten game at Autzen Stadium in Eugene. Kickoff is scheduled for 9 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s college football odds around the Michigan State vs. Oregon odds, and make our expert college football picks and predictions.

The Spartans are in the middle of a tough 3-game stretch. Michigan State lost 23-19 at Boston College Sept. 21, although it covered as a 5-point underdog, while it lost 38-7 as 23.5-point home dogs against 3rd-ranked Ohio State last weekend. The Under has cashed in 3 in a row for MSU, and 4 of 5 games this season.

Michigan State has posted a 1-1 straight up (SU) mark in 2 road games, but it is 2-0 against the spread (ATS), while splitting the Over-Under.

While the Ducks are undefeated, they’re just 1-3 ATS. At home, they’re 2-0 ATS, averaging 30.5 points per game (PPG), allowing 24.0 PPG with a 1-1 O/U record. The Ducks have scored 34 or more points in their last 3 games, while allowing 14 or fewer points in 3 of their 4 outings.

The last time these teams met was in the Redbox Bowl in Santa Clara, Dec. 31, 2018, with Oregon edging Michigan State 7-6. The Vegas line was Pick with the Under (45.5) easily cashing … but that was 6 years ago.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Michigan State at Oregon odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Thursday at 7:48 p.m. ET.

  • Moneyline (ML): Michigan State +1200 (bet $100 to win $1,200) | Oregon -3000 (bet $3,000 to win $100)
  • Against the spread: Michigan State +23.5 (-110) | Oregon -23.5 (-110)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Michigan State at Oregon picks and predictions

Prediction

Oregon 45, Michigan State 17

Moneyline

Oregon (-3000) will cost 30 times the potential return. That’s obviously way too risky for not nearly enough reward. In other words, you must risk $100 for every $3.33 of profit. There is never a reason to justify betting such a heavy, heavy underdog.

PASS.

Against the spread

OREGON -23.5 (-110) is worth a look laying the points at home. Michigan State is experiencing a very difficult stretch, facing a top-10 team for a 2nd consecutive game in a 6-day span.

We saw Ohio State drop Sparty 38-7 last Saturday in East Lansing, and it’s hard to envision Michigan State faring much better against Oregon’s high-octane offense.

The Ducks have scored 34 or more points in all 3 of their games against FBS this season, while the Spartans have scored 19 or fewer points in 3 of their 4 games vs. FBS foes. QB Aidan Chiles has a bright future for Michigan State, but he and the offense is a bit limited at the moment.

Over/Under

OVER 52.5 (-110) might be the best play on the board as Oregon has the potential to take care of most of this number on its own.

The Over has cashed in 2 of the past 3 games for the Ducks, and their lone home game vs. an FBS opponent this season finished with 71 combined points — with Oregon beating Boise State 37-34 Sept. 7.

BET OVER 52.5 and feel confidently in doing so.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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First look: Michigan State vs. Oregon odds and lines

Looking at Friday’s Michigan State at Oregon college football odds, lines and trends. Here’s what you need to know.

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The Michigan State Spartans (3-2, 1-1 Big Ten) and the No. 6 Oregon Ducks (4-0) meet at Autzen Stadium Friday. Kickoff is slated for 9 p.m. ET (FOX). Below, we look at Michigan State vs. Oregon odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Michigan State dropped their Big Ten home opener to 3rd-ranked Ohio State Saturday, losing 38-7. The Spartans failed to cover as 23.5-point underdogs with the Under (48.5) cashing. Michigan State’s offense struggled, turning the ball over 3 times and finishing with 246 total yards (199 passing, 47 rushing), while the defense allowed 483 yards (298, 185).

Oregon remained undefeated with a 34-13 victory at UCLA in their Big Ten opener. However, the Ducks didn’t cover as 23.5-point underdogs and as  the Under (54.5) hit. QB Dillon Gabriel led the way with 278 passing yards, 3 TDs and an interception, with WR Tez Johnson accounting for 121 yards and 2 scores. The Ducks defense was dominant, limiting UCLA to just 172 total yards (125 passing, 47 rushing).

– RankingsUS LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

Stream select live college football games and full replays: Get ESPN+

Michigan State vs. Oregon odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated Sunday at 6:23 p.m. ET.

  • Moneyline (ML): Off the board
  • Against the spread (ATS): Michigan State +24.5 (-110) | Oregon -24.5 (-110)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

FanDuel Sportsbook lists a ML of:

  • Michigan State +1280 (bet $100 to win $1,280)
  • Oregon -3500 (bet $3,500 to win $100)

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2024 betting stats

  • ML: Michigan State 3-2 | Oregon 4-0
  • ATS: Michigan State 2-3 | Oregon 1-3
  • O/U: Michigan State 1-4 | Oregon 2-2

Michigan State vs. Oregon head-to-head

Oregon holds a 4-3 edge in their all-time series with Michigan State with each team owning a 3-0 advantage on their home field.

The most recent clash was on a neutral field when Oregon claimed a narrow 7-6 victory with a 4th-quarter TD pass by QB Justin Herbert in the in the 2018 Redbox Bowl. The spread was a pick ’em, and the total stayed comfortably Under the 45.5-point O/U line.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @DrewPhelps05 on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

College sports coverage from USA TODAY Sports Media Group:
Alabama / Arkansas / Auburn / Clemson / Colorado / DukeFlorida / Florida StateGeorgia / Iowa / KentuckyLSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Rutgers / Tennessee / Texas / Texas A&M / UCLA / USC / WashingtonWisconsin / Recruiting / Transfer portal / College Football Playoffs / College Sports Wire / High School

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