The No. 9 Michigan State Spartans (6-0, 3-0 Big Ten) and Indiana Hoosiers (2-3, 0-2) tangle in a Saturday noon ET game at Memorial Stadium in Bloomington, Ind. Below, we look at the Michigan State vs. Indiana odds and lines; check back for our college football picks and predictions.
Rankings courtesy of AFCA Coaches Poll powered by USA TODAY Sports.
Michigan State remained undefeated with a 31-13 win at Rutgers. The MSU defense was solid in bouncing back after allowing 31 points to Western Kentucky in the previous game (Oct. 2). The Spartans held the Scarlet Knights to just 3.1 rushing yards per carry and a 5-of-19 performance on third and fourth downs. With players like DE Jacub Panasiuk (18 tackles, 4.5 sacks, 1 forced fumble) leading the way, Michigan State has allowed just 19.7 points per game to rank 27th in the country.
The Hoosiers are coming off a bye week, which followed a 24-0 loss to now-No. 8 Penn State Oct. 2. IU’s schedule has been tough as the other conference loss was to Iowa. That one was a 34-6 setback Sept. 4, so Indiana has scored just 6 points through eight quarters of Big Ten play. IU’s struggling offense – ranked 107th FBS in total yards – figures to get better the rest of the season. A big key will be the status of the QB Michael Penix, Jr., who left IU’s last game with a separated shoulder. It’s unknown if he will play Saturday.
Michigan State at Indiana odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 4:49 p.m. ET.
- Money line: Michigan State -200 (bet $200 to win $100) | Indiana +160 (bet $100 to win $160)
- Against the spread (ATS): Michigan State -4.5, -105 (bet $105 to win $100) | Indiana +4.5, -115 (bet $115 to win $100)
- Over/Under (O/U): 51.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)
Also see: Betting 101
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2021 betting stats:
- ML: Michigan State 6-0 | Indiana 2-3
- ATS: Michigan State 4-0-2 | Indiana 1-4
- O/U: Michigan State 3-3 | Indiana 3-2
Michigan State at Indiana head-to-head
MSU had four turnovers and just 191 total yards in last year’s 24-0 shutout loss to Indiana. Michigan State had won 10 of the previous 11 series meetings. In a series that dates back to 1922, the Spartans are 48-17-2 against IU.
The Spartans are 12-5 ATS across their last 17 games against the Hoosiers. In the last 13 meetings, the Over is 10-3.
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