Miami-Florida at Louisville odds, picks and best bets

Previewing Saturday’s Miami Hurricanes at Louisville Cardinals sports betting odds and lines, with college football betting picks, tips and best bets.

The Miami Hurricanes (1-0) and the Louisville Cardinals (1-0) meet at Cardinal Stadium in Louisville, Ky. with a 7:30 p.m. ET kickoff Saturday. We analyze the Miami-Louisville college football betting odds and lines, with picks and best bets.

The Cardinals are ranked 16th in the Amway Coaches Poll powered by USA TODAY Sports, while the Hurricanes are ranked 18th.

Miami at Louisville: Betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 4:15 p.m. ET.

  • Money line: Louisville -134 | Miami +110
  • Against the spread/ATS: Louisville -2.5 (-115) | Miami +2.5 (-106)
  • Over/Under: 64.5 (O: -110 | U: -110)

Miami at Louisville: Three things to know

  1. Last week in a 31-14 win vs. UAB the Hurricanes debuted their new spread offense under the tutelage of offensive coordinator Rhett Lashlee. It’s the first time in program history the team is employing the spread.
  2. The new offense is still a work in progress, as Hurricanes QB D’Eriq King opened with one touchdown pass and one rushing touchdown, but the stats overall weren’t eye-popping. He ran for 83 yards, or 6.9 yards per attempt while throwing for 144 yards. RB Cam’Ron Harris was the big man on campus, rambling for 134 yards and two scores.
  3. Cardinals QB Malik Cunningham did have eye-popping stats in last week’s 35-21 win over Western Kentucky. He went for 343 passing yards, three touchdowns and a pick while rushing for 24 yards and another score.

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Miami at Louisville: Odds, betting lines and picks

Prediction

Louisville 34, Miami 27

Money line (ML)

Money line plays in college football are not my favorite thing, but occasionally a situation will come up where it is fairly attractive. LOUISVILLE (-134) isn’t a lot of vig to just take them straight up on their home field. Their rushing defense is stout, and they won’t let Miami’s Harris gouge them for big yards like UAB did a week ago.

Against the Spread (ATS)

LOUISVILLE (-2.5, -110) just needs to win by a field goal to cash this ticket. As long as the line remains under three points it’s especially attractive. Miami (+2.5, -110) is just 8-8 ATS in their past 16 road games, so they need to prove they can win consistently on the road and they’re a different team before you start backing them. Meanwhile, the Cards have won four in a row at home, including last week.

Over/Under (O/U)

The oddsmakers are expecting a higher-scoring game, but UNDER 64.5 (-110) is the play. Miami allowed just 14 points against UAB last week, and they gifted them seven points in the first quarter with a turnover deep in their own territory. The Under is 6-0 in Miami’s past six as a road underdog, and 16-7-2 in their past 25 ACC games over the past three seasons. While the Over is 4-1 in Louisville’s past five as a home favorite, Miami’s defense will hold Cunningham down just a little bit.

Also see:

  •  CFN – The latest college football coverage

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