Seattle Mariners at Washington Nationals Game 2 odds, picks and predictions

Analyzing Wednesday’s Seattle Mariners at Washington Nationals Game 2 odds and lines, with MLB expert picks and predictions.

The Seattle Mariners (45-42) and Washington Nationals (30-58) play the second game of an interleague doubleheader Wednesday at Nationals Park. First pitch is scheduled for 6:05 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Mariners vs. Nationals Game 2 odds with MLB picks and predictions.

This analysis posted prior to Tuesday’s first game between Seattle and Washington.

This double-header will mark the first time the clubs have met this season.

The Mariners and Nationals were washed out in Tuesday’s interleague series opener, so now they’ll play two Wednesday. The M’s have played just one doubleheader this season, losing both games in a matchup at home against the Los Angeles Angels June 18.

The Nationals swept their first double dip April 19 against the Arizona Diamondbacks, but have lost in the second game of their 2 other doubleheaders this season.

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Mariners at Nationals projected starters

LHP Tommy Milone vs. RHP Erick Fedde

Milone (0-1, 3.60 ERA) makes his 1st start and 5th appearance. He has allowed 7 H and 0 BB with 4 K through 10 IP.

  • Has made 2 relief appearances on the road this season, allowing 2 ER and 3 H in 3 IP.
  • Returns to Washington where he made his major league debut in 2011, and returned to make 5 appearances in the 2018 season.

Fedde (5-6, 5.01 ERA) makes his 18th start. He has a 1.49 WHIP, 4.4 BB/9 and 7.2 K/9 through 82 2/3 IP.

  • Is 2-3 with a 4.60 ERA and .253 opponent batting average with 43 K across 45 IP in 9 starts at home this season.
  • Has posted a 1-0 record with a 1.80 ERA across 15 IP in 3 starts against American League opponents in 2022.

Mariners at Nationals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:57 a.m. ET.

  • Money line (ML): Mariners -117 (bet $117 to win $100)  | Nationals -103 (bet $103 to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners -1.5 (+130) | Nationals +1.5 (-160 )
  • Over/Under (O/U): 9.5 (O: -107 | U: -115)

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Mariners at Nationals picks and predictions

Prediction

Nationals 4, Mariners 2

Money line

The NATIONALS (-103) are a strong play in the back end of the doubleheader behind Fedde. Yes, Fedde was turned up for 8 runs last time out in Atlanta, serving up 3 homers in the process, but he had allowed 3 or fewer runs in each of his prior 4 outings and won 2 of them.

Milone isn’t stretched out and this will be a bullpen game for the Mariners. That’s not a good thing in the second end of a double dip.

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Run line/Against the spread

The ALTERNATE RUN LINE NATIONALS -1.5 (+185) is worth a small-unit play as a bet against the team’s former southpaw Milone. Washington hasn’t won a ton of games this season, but it will get the best of the left-hander.

Over/Under

The UNDER 9.5 (-115) is the lean in Game 2.

Entering Wednesday, the Under is 5-2 in the last 7 starts for the M’s against a right-handed starting pitcher.

For the Nats, the Under is 5-2 in the last 7 home games, while going 5-1 in the past 6 interleague games — not counting Game 1 of this doubleheader.

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Seattle Mariners at Washington Nationals odds, picks and predictions

Analyzing Tuesday’s Seattle Mariners at Washington Nationals odds and lines, with MLB expert picks and predictions.

The Seattle Mariners (45-42) and the Washington Nationals (30-58) open a 2-game interleague set Tuesday at Nationals Park in Washington, D.C. First pitch is scheduled for 7:05 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Mariners vs. Nationals odds with MLB picks and predictions.

Season series: This is the first meeting since May 2017.

The Mariners have rattled off 8 consecutive victories, including four 1-run games. Seattle is 6-5 in 11 interleague games this season.

The Nationals are in a tailspin, dropping 4 straight outings, and 9 of the previous 10 contests. Washington is 5-6 in interleague play.

Mariners vs. Nationals projected starters

RHP Chris Flexen vs. RHP Josiah Gray

Flexen (5-8, 4.00 ERA) makes his 17th start of the season. He has a 1.40 WHIP, 3.2 BB/9 and 6.6 K/9 through 90 IP.

  • Is 2-5 with a 4.07 ERA with a .257 opponent batting average with 34 K across 48 2/3 IP in 9 road outings.
  • Picked up a win with 6 2/3 scoreless IP, 4 H, 3 BB and 8 K at the San Diego Padres July 4 in his most recent interleague start.

Gray (7-5, 4.14 ERA) makes his 17th start of the season. He has a 1.24 WHIP, 3.7 BB/9 and 10.2 K/9 through 87 IP.

  • Is 2-5 with a 6.42 ERA across 40 2/3 IP in 8 starts at Nationals Park and 5-0 with a 2.14 ERA in 8 starts on the road.
  • Is 1-1 with a 5.40 ERA with 17 K through 18 2/3 IP across 3 starts vs. AL opponents this season.

Mariners vs. Nationals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:07 a.m. ET.

  • Money line (ML): Mariners -108 (bet $108 to win $100) | Nationals -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): Mariners -1.5 (+145) | Nationals +1.5 (-180)
  • Over/Under (O/U): 9.5 (O: -110 | U: -110)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Mariners vs. Nationals picks and predictions

Prediction

Mariners 6, Nationals 5

Money line

The MARINERS (-108) are red-hot right now with 16 wins in their last 19 games and while cashing in 8 of their last 9 road outings. Seattle has also picked up a victory in 14 of its last 17 outings against a right-handed starting pitcher.

Gray has also struggled at home and it is hard to envision him cooling off the M’s right now.

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Run line/Against the spread

The Nationals +1.5 (-180) are a little on the expensive side if you’d like a little insurance. Washington wouldn’t be a terrible play if the price was right, as Seattle has won 4 of its 8 games during the win streak by 1 run.

PASS.

Over/Under

The OVER 9.5 (-110) is the lean in the interleague opener.

The Over has hit in 4 straight series openers for the Mariners while going 20-5-1 in their last 26 interleague road games.

The Under has dominated for Washington lately, but Gray has been giving at home, and the Nats should be able to get to Flexen for a few.

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Kevin J. Erickson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball
BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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