Louisiana at Iowa State odds, picks and best bets

Previewing Saturday’s Louisiana Ragin’ Cajuns at Iowa State Cyclones sports betting odds and lines, with college football betting picks, tips and best bets.

The season opens for the Louisiana Ragin’ Cajuns and the Iowa State Cyclones at Jack Trice Stadium in Ames, Iowa, with a Saturday noon ET kickoff. We analyze the Louisiana-Iowa State college football betting odds and lines, with picks and best bets.

Louisiana at Iowa State: Betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 12:22 a.m. ET.

  • Moneyline: Iowa State -400 | Louisiana +315
  • Against the spread/ATS: Iowa State -11.5 (-110) | Louisiana +11.5 (-110)
  • Over/Under: 56 (O: -110 | U: -110)

Louisiana at Iowa State: Three things to know

  1. Iowa State returns one of the more decorated quarterbacks in the Big 12, as Brock Purdy threw for 3,982 yards, 27 touchdowns and nine interceptions while completing 65.7 percent of his pass attempts in 2019, and he ran for 249 yards and eight more scores.
  2. The Ragin’ Cajuns rolled up 501.3 total yards per game, ranking eighth in the nation, and they were seventh overall with 265.3 yards per game on the ground. QB Levi Lewis threw for 3,050 yards, 26 touchdowns and just four interceptions, so they are anything but one dimensional.
  3. Louisiana’s two-headed rushing attack of RB Elijah Mitchell (1,147 yards, 16 touchdowns in 2019) and RB Trey Ragas (820 yards, 11 touchdowns in 2019) will also be a handful for an ISU rush defense which ranked 33rd in the land last season.

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Louisiana at Iowa State: Odds, betting lines and picks

Prediction

Iowa State 44, Louisiana 34

Moneyline (ML)

Iowa State (-400) is playing with fire in their opener, scheduling a very dangerous Louisiana (+315) team from the Sun Belt Conference. The Cajuns won 10 games last season, including their bowl game, and they boast a high-octane offense with all of their key members returning. It’s not inconceivable that Louisiana can go to Jack Trice and win outright, so AVOID potentially risking and losing four times your return.

Against the Spread (ATS)

LOUISIANA (+11.5, -110) catching double digits in this one is a very nice surprise. This is one of the highest-octane offenses that the Cyclones might face all season. They Cajuns are balanced, too. So, if they do fall behind early, they can ride the arm of Lewis. If they get ahead, their two-headed rushing attack can be dangerous. Iowa State has one of the top quarterbacks in the nation, so this will be fun.

Over/Under (O/U)

The OVER 56 (-110) is a slam-dunk play here. Iowa State scored 34.1 points per game in 2019, and allowed 25.3. Louisiana rolled up 38.8 PPG to rank 11th in the country. The scoreboard operator in Ames better be ready, because both of these potent offenses will be able to score plenty.

Also see:

  •  CFN – The latest college football coverage

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