First look: Detroit Lions at Carolina Panthers odds and lines

Looking at Saturday’s Detroit Lions at Carolina Panthers odds, lines and trends. Here’s what you need to know.

The Detroit Lions (7-7) and the Carolina Panthers (5-9) meet for a Week 16 battle Saturday at Bank of America Stadium in Charlotte. Kickoff is at 1 p.m. ET (FOX). Below, we look at Lions vs. Panthers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The underdog Lions (+2.5) edged the New York Jets 20-17 on the road in Week 15, winning for the 6th time in the lst 7 games, while going 7-0 ATS during the impressive run. Detroit currently sits just a half-game back of a wild-card spot in the NFC.

The Panthers are 4 games under .500, but still just 1 game back in the dismal NFC South, so this is an important game for both teams. Carolina lost 24-16 as 2.5-point favorites at home to the Pittsburgh Steelers, blowing a chance to pull into a 1st-place tie with the Tampa Bay Buccaneers.

Also seeAll Week 16 odds and lines

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Lions at Panthers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2:45 a.m. ET.

  • Moneyline (ML): Lions -155 (bet $155 to win $100) | Panthers +135 (bet $100 to win $135)
  • Against the spread (ATS): Lions -3 (-109) | Panthers +3 (-111)
  • Over/Under (O/U): 44 (O: -110 | U: -110)

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2022 betting stats

  • ML: Lions 7-7 | Panthers 5-9
  • ATS: Lions 10-4 | Panthers 7-7
  • O/U: Lions 9-5 | Panthers 6-8

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Lions at Panthers head-to-head

The Panthers won 20-0 in the most recent meeting in Charlotte on Nov. 22, 2020. The Panthers have won 3 of the last 4 in this series, while also going 3-1 ATS during the span. The Under is 3-1 in the last 4 meetings.

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