Best NFL underdog picks and predictions for Week 15

Analyzing NFL Week 15 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Week 15 kicks off with the LA Rams as road underdogs against the San Francisco 49ers on Thursday night. Last week, 7 underdogs covered the spread in their games, while only 3 pulled off the outright upset.

Our 3 best underdog picks went 2-1 last week, as the New York Jets covered the 6.5-spread in a 32-26 overtime loss to the Miami Dolphins and the Carolina Panthers covered the 14-point spread in a 22-16 loss to the Philadelphia Eagles. But the Chicago Bears did not cover the 4-point spread as underdogs against the 49ers, as they were blown out 38-13.

On the season, we are 22-19-1 on our underdog picks of the week.

Time for some more! Below, we analyze BetMGM Sportsbook’s NFL odds, and tab the best NFL Week 15 underdog bets to cash in on among SportsbookWire’s NFL expert picks and predictions.

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NFL underdog predictions: Week 15

Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Thursday at 1:18 p.m. ET. All games Sunday and ET unless noted.

RAMS (+125) at 49ers – Thursday 8:15 p.m. (Amazon Primer Video)

The 49ers will not have LT Trent Williams and likely will be on their fourth-string running back as Christian McCaffrey and Jordan Mason are on injured reserve and rookie RB Isaac Guerendo is questionable with a sprained foot on a short week. DE Nick Bosa might return, but no Williams means pass rushers Braden Fiske and Byron Young will be able to harass 49ers QB Brock Purdy. 

The Rams are 5-2 in their last 7 games and have beaten the 49ers in their last 2 meetings. Their last 5 covers have been outright wins.

The 49ers have lost their last 3 games against teams with winning records.

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Ravens at GIANTS +16 (-110) – 1 p.m. (CBS)

The Ravens have only 2 wins of more than 16 points. Both games were against teams expected to make the playoffs. They are 6-6-1 ATS this season. They are 1-3 ATS in their last 4 games.

The Giants covered the 5.5-point spread in a 3-point loss to the New Orleans Saints last week, snapping a 7-game ATS losing streak. However, only 3 of their losses have been by more than 16 points.

Sixteen points is just a huge spread.

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DOLPHINS +3 (-110) at Texans – 1 p.m. (CBS)

The Texans have just 1 win by more than 3 points in their last 7 games. Housotn has averaged 23.6 points per game over those 7 games.

The Dolphins have won 4 of their last 5 games and have averaged 27.7 points per game since the return of QB Tua Tagovailoa. 

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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