First look: Kansas City Chiefs at Los Angeles Chargers odds and lines

Looking at Sunday’s Kansas City Chiefs at Los Angeles Chargers Week 11 NFL odds, lines and trends. Here’s what you need to know.

The Kansas City Chiefs (7-2) head to SoFi Stadium to take on the Los Angeles Chargers (5-4) in Week 11. Kickoff on Sunday is set for 8:20 p.m. ET (NBC). Below, we look at Chiefs vs. Chargers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Chiefs are coming off their 3rd win in a row. They beat the Jacksonville Jaguars 27-17 in Week 10, taking 1st place in the AFC thanks to a Buffalo Bills loss. QB Patrick Mahomes (26-for-35, 331 yards, 4 TDs, 1 INT, 39 yards rushing) found newly acquired WR Kadarius Toney in the end zone for the first time in Toney’s career, while TE Travis Kelce earned 81 yards and 1 TD on 6 catches.

While 7-2 overall, Kansas City is just 3-5-1 ATS this season. The Chiefs also haven’t covered the spread against an AFC opponent in 2022 — all 3 covers came against the NFC West.

The Chargers lost 22-16 to the San Francisco 49ers on Sunday night. QB Justin Herbert had just 196 yards passing, 1 TD and 1 INT while Chargers RBs rushed for a total of 29 yards. It was a rough day for Los Angeles, which has a banged up squad — the team was missing WRs Mike Williams and Keenan Allen along with LB Joey Bosa due to injuries.

Despite frequent injuries, L.A. has been good at covering the spread this season at 6-3 ATS. The Chargers were favorites in all 3 matchups that they failed to cover this season.

Also see: All Week 11 odds and lines

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Chiefs at Chargers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2:39 p.m. ET.

  • Moneyline (ML): Chiefs -310 (bet $310 to win $100) | Chargers +255 (bet $100 to win $255)
  • Against the spread (ATS): Chiefs -7 (-108) | Chargers +7 (-112)
  • Over/Under (O/U): 49.5 (O: -111 | U: -109)

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2022 betting stats

  • ML: Chiefs 7-2 | Chargers 5-4
  • ATS: Chiefs 3-5-1 | Chargers 6-3
  • O/U: Chiefs 4-5 | Chargers 4-5

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Chiefs vs. Chargers head-to-head

This AFC West rivalry dates all the way back to 1960. The Chiefs lead the overall series 66-58-1. Under the leadership of Mahomes, the Chiefs are 6-2 against the Chargers. Mahomes has 18 TDs and 5 INTs with an average of 258 yards passing per game in those 8 games against the Chargers.

Meanwhile, the Chargers are 2-3 against the Chiefs with Herbert at the helm, though Chad Henne was the starting QB for the Chiefs for one of those victories. In those 5 games, Herbert has 13 TDs, 3 INTs, 3 rushing TDs and an average of 293 yards passing per game.

The last time these teams played was Week 2. The Chiefs won 27-24 but did not cover the spread as 4-point favorites.

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Thursday Night Football picks and prop bets: A genuinely meaningful Chiefs-Chargers game? On Thursday night?

The AFC West may be decided on a Thursday night. Wild.

The fate of the AFC West may be determined in Week 15. And it may be determined in the very spot the NFL typically reserves for throwaway Jacksonville Jaguars games.

Thursday Night Football will host a marquee matchup with major playoff implications when the Los Angeles Chargers play host to the Kansas City Chiefs. The game is a lens to provide clearer sight on several different questions.

Is this Chiefs team a worthy successor to the two-time AFC champions that preceded it? Was the Kansas City defense able to fix itself, in season, without any major additions?

Should the Chargers be taken seriously as contenders, or are they hanging around just long enough for their self-sabotage to be entirely devastating to a jaded fanbase, as tradition dictates? Is Justin Herbert ready to join the NFL’s protected class of elite quarterbacks?

That last question could decide whether Los Angeles takes over first place in the division in hopes for its first West title since 2009 or whether the status quo remains unchanged. We’ve got a game that could shape the road to the Super Bowl in Week 15, and we’re getting it on a Thursday night. Sometimes the Football Gods shine upon us.

Let’s talk about their bounty. All odds via Tipico.