Best NFL underdog picks and predictions for Week 16

Analyzing NFL Week 16 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

In Week 15, only 4 underdogs won their games outright. However, 9 covered the spread. That included the Indianapolis Colts, who covered the 3.5-point spread in the greatest collapse in NFL history, as they saw a 33-0 lead turn into a 39-36 overtime loss.

Below, we analyze analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 16 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

As for my underdog picks, 2 of the 3 teams covered. The Houston Texans covered the 14-point spread in a 30-24 overtime loss to the Kansas City Chiefs, the New York Giants beat the Washington Commanders 20-12 outright as 4-point underdogs, but the Tampa Bay Buccaneers lost 34-13 to the Cincinnati Bengals, failing to cover the 3.5-point spread.

Overall this season, my underdog picks are 21-24. Here we go for this week’s picks.

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NFL underdog predictions: Week 16

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at Thursday at 11:08 a.m. ET. All games Saturday and ET unless noted.

JACKSONVILLE JAGUARS (+115) at New York Jets – Thursday, 8:15 p.m. (Prime Video)

The Jaguars have won 3 of their last 4 games, including a 40-34 overtime win last week over the Dallas Cowboys. They have scored 28 or more points in those 3 wins. QB Trevor Lawrence has 7 TD passes and 1 INT in the last 2 weeks.

The Jags are 3-0-1 ATS in their last 4 games against AFC teams.

The Jets have lost 3 in a row and 4 of their last 5, averaging 13.5 points in their losses.

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SEATTLE SEAHAWKS +10 (-112) at Kansas City Chiefs – 1 p.m. (FOX)

The Chiefs have yet to cover the spread in a home game this season. They are 0-5-1 ATS on their home field.

The Seahawks have lost by double digits only once this season — in Week 2 27-7 to the NFC West champion San Francisco 49ers.

The Chiefs have won by more than 10 points only once in their last 6 games.

The Seahawks are 7th in scoring this season, averaging 25.4 points per game. They will be able to keep up with the Chiefs and their No. 1 scoring offense.

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ATLANTA FALCONS +7 (-106) at Baltimore Ravens –  1 p.m. (FOX)

The Falcons are 8-6 ATS this season and have lost by more than 7 points only once in the last 7 weeks.

Five of the Ravens’ 9 wins have been by less than 7 points. They have only 1 win in their last 5 games by more than 7.

The Ravens have not covered the spread this season at home, going 0-5-1 ATS there.

More NFL Week 16 picks and predictions

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